Pain Flashcards

1
Q

FeverAll/Ofirmev

A
  • APAP
  • FeverAll - rectal suppository formulation
  • Ofirmev - injection
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Lorcet/Lortab

A
  • Hydrocodone + APAP

- Also Vicodin and Norco

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Endocet

A
  • Oxycodone + APAP

- Percocet

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Excedrin Tension HA

A

APAP + Caffeine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Excedrin Extra Strength

A
  • APAP + ASA + Caffeine

- Also Excedrin Migraine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Midol Complete

A

APAP + Caffeine + Pyrilamine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

NAC

A
  • N-acetylcysteine, antidote for APAP overdose
  • Glutathione precursor, increases glutathione
  • Administered IV or PO
  • Rumack-Matthew nomogram used to determine likelihood of hepatotoxicity and if NAC is needed
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Cadalor

A
  • Ibuprofen
  • Also Advil and Motrin B
  • Max of 3.2 g/d
  • 200-400 mg for adult dosing Q4-6H
  • Limit self-treatment <10 days
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Indocin

A
  • Indomethacin

- High risk for CNS side effects

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Vimovo

A
  • Naproxen + esomeprazole

- Naproxen can sometimes be dosed BID

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Toradol

A
  • Ketorolac
  • Oral and NS formulation
  • Max of 5 days duration combined for lifetime
  • Warning: acute renal and hepatic failure
  • Prime NS 5 times before use
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Celebrex

A
  • Celecoxib
  • CI: Sulfonamide allergy
  • Highest COX-2 selectivity
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Voltaren

A
  • Diclofenac
  • Max of 32 g/d total body
  • Patch can be applied BID
  • Box Warning: Avoid Arthrotec formulation in childbearing females (contains misoprostol)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Agents with SOME COX-2 Selectivity

A
  • Meloxicam (Mobic)

- Nabumetone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Ascriptin

A
  • ASA + Acetylsalicylic acid
  • Also Bufferin or Ecotrin
  • All EC/buffered
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Excedrin

A

APAP + ASA + Caffeine

-Also Excedrin Migraine

17
Q

Yosprala

A

-ASA + Omeprazole

18
Q

Doan’s Extra Strength

A
  • Magnesium Salicylate

- Non-acetylated salicylates

19
Q

Salicylate NSAID Information

A
  • Salicylate overdose can cause tinnitus
  • Methyl salicylate is popular OTC topical in BenGay, IcyHot, and Salonpas
  • Take ASA 1 hour before or 8 hours after ibuprofen if being used together
  • NSAIDs in general can increase the levels of lithium
20
Q

Opioids with Alcohol Boxed Warning

A
  • Kadian
  • Nucynta ER
  • Oxymorphone ER
  • Zohydro ER
21
Q

Codeine Classes

A
  • CII: Codeine tablet
  • CIII: tablet/capsule combination products
  • CV: oral solution combination products
22
Q

Codeine Information

A
  • Risk of respiratory depression and death in ultra-rapid metabolized of CYP2D6 polymorphism
  • Don’t use in kids < 12 or kids < 18 following tonsillectomy/adenoidectomy
  • SE: Constipation
23
Q

Sublimaze

A
  • Fentanyl, Duragesic is also a brand name
  • Actiq: transmucosal lozenge on stick (lollipop)
  • 1 patch Q72H
24
Q

Fentanyl Information

A
  • CYP3A4i
  • SE: Application site redness/erythema
  • Only potential to use in patients on 60 mg or morphine or more for at least 7 days
  • Similar drug is remifentanil (IV)
  • Apply to hairless skin (cut hair if necessary)
  • Only cover w/ permitted adhesives: Bioclusive, Tegaderm
25
Q

Dilaudid

A
  • Hydromorphone
  • Oral: 2-4 mg Q4-6H PRN
  • IV: 0.2-1 mg Q2-3H PRN
26
Q

Hydromorphone Information

A
  • Boxed Warning: Medication error with high potency (use in opioid tolerant ONLY)
  • High risk for overdose
27
Q

Dolophine

A
  • Methadone
  • Box Warning: QT prolongation (life-threatening)
  • Variable half-life
  • Decreases testosterone and can cause sexual dysfxn
  • Major CYP3A4 substrate (avoid with inhibitors)
28
Q

Demerol

A
  • Meperidine
  • Warning: renal impairment/elderly at risk for CNS toxicity
  • No longer recommended as an analgesic
  • Short duration
  • Metabolite is renally cleared and can accumulate/induce seizures
  • Serotonergic, increased 5HT syndrome risk
29
Q

Kadian

A
  • Morphine
  • ER formulation, MS Contin is another one
  • Injection: Duramorph, Infumorph
  • SE: Pruritus
  • Diphenhydramine can be used to prevent histamine-induced pruritis
30
Q

Roxicodone

A
  • Oxycodone
  • IR formulation
  • CR: OxyContin, Endocet or Percocet is + APAP
  • Box warning: CYP3A4i
  • SE: Pruritus
31
Q

Opana

A
  • Oxymorphone

- Take on an empty stomach!

32
Q

IV/IM Opioid Conversions

A

Morphine 10 mg : Hydromorphone 1.5 mg

33
Q

Oral Opioid Conversions

A

Morphine 30 mg : Hydromorphone 7.5 mg : Oxycodone 20 mg

34
Q

Opioid Allergy

A

Tend to Cross-React:

  • Codeine
  • Hydrocodone
  • Oxycodone
  • Morphine
  • Hydromorphone
  • Oxymorphone
  • Buprenorphine
  • Heroin