Packet 8 - Circulatory Function Part 2 (4) Flashcards

1
Q

II Mechanics of breathing

A
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2
Q

Gas Exchange

Transport of oxygen/carbon dioxide across alveolar capillary membrane. Influenced by partial pressure of the gas, surface area, and thickness of membrane.

a. ) Ventilation
b. ) Perfusion
c. ) Diffusion

A

c.) Diffusion

Transport of oxygen/carbon dioxide across alveolar capillary membrane. Influenced by partial pressure of the gas, surface area, and thickness of membrane.

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3
Q

Gas Exchange

Move venous blood through pulmonary capillaries adjacent to alveoli.

a. ) Ventilation
b. ) Perfusion
c. ) Diffusion

A

b.) Perfusion

Move venous blood through pulmonary capillaries adjacent to alveoli.

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4
Q

Gas Exchange

Movement of air into and out of alveoli.

a. ) Ventilation
b. ) Perfusion
c. ) Diffusion

A

a.) Ventilation

Movement of air into and out of alveoli.

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5
Q

Occurs when areas of the lungs are perfused, but not ventilated. Blood is being pushed from the venous circulation to the arterial circulation without it being oxygenated first.

a. ) dead air space
b. ) shunt

A

b.) shunt

Blood is being shunted from the venous circulation to the arterial circulation without it being oxygenated first.

P/C factors: collapse of alveoli; airway obstruction; decrease in chest expansion; depression of respiratory center

blood, no oxygen

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6
Q

Occurs when areas of the lungs are ventilated, but not perfused. Blood is occluded/blocked, but air is present. Since there is no blood, gas exchange does not occur.

a. ) dead air space
b. ) shunt

A

a.) dead air space

Occurs when areas of the lungs are ventilated, but not perfused. Blood is occluded/blocked, but air is present. Since there is no blood, gas exchange does not occur.

P/C factors: Thromboembolism (pulmonary embolism); severe vasoconstriction

oxygen, no blood

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7
Q

Diffusion

If there is a decrease in surface area, what happens to diffusion?

A

Decrease in surface area → decrease in diffusion

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8
Q

Diffusion

If there is an increase in surface area, what happens to diffusion?

A

increase in surface area → increase in diffusion

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9
Q

Diffusion

If there is an increase in the thickness of the membrane, what happens to diffusion?

A

increase in thickness of membrane → decrease in diffusion

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10
Q

Diffusion

If there is a decrease in the thickness of the membrane, what happens to diffusion?

A

decrease in thickness of membrane → increase in diffusion

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11
Q

Oxygen Transport

Oxygen is found in blood in two forms: in a dissolved state and in combination with hemoglobin in RBC. When oxygen is in its dissolved state, oxygen dissolves in plasma as it moves into and out of RBCs, and is represented by ______.

a. ) PaO2
b. ) SaO2

A

a.) PaO2

Dissolved state

oxygen dissolves in plasma as it moves into and out of RBCs, and is represented by PaO2

Only 1% of oxygen is in this state

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12
Q

Oxygen Transport

Oxygen is found in blood in two forms: in a dissolved state and in combination with hemoglobin in RBCs. When oxygen is found in combination with hemoglobin in RBCs, and it is represented by ______.

a. ) PaO2
b. ) SaO2

A

b.) SaO2

in combination with hemoglobin in RBCs

  • 98-99% of oxygen is carried this way*
  • Measures % of Hgb that is carrying oxygen*
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13
Q

Oxygen Transport

Oxygen bound to hemoglobin cannot be used in tissue metabolism, it must be released in order to be used.

When PO2 gets to _____ mm Hg, Hgb releases oxygen.

A

When PO2​ gets to 60 mm Hg, Hgb releases oxygen.

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14
Q

Oxygen Transport

Oxygen bound to hemoglobin cannot be used in tissue metabolism, it must be released in order to be used.

A ______ occurs in conditions that favor oxygen binding.

(Hgb affinity for oxygen increases → PO2 has to drop lower to trigger oxygen release, occurs when tissues don’t need as much oxygen)

a. ) shift to the left
b. ) shift to the right

A

shift to the right

A shift to the right occurs in conditions that favor oxygen binding.

Hgb affinity for oxygen increases

PO2 has to drop lower to trigger oxygen release, occurs when tissues don’t need as much oxygen)

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15
Q

Oxygen Transport

Oxygen bound to hemoglobin cannot be used in tissue metabolism, it must be released in order to be used.

A ______ occurs in conditions that favor oxygen release.

(Hgb affinity for oxygen decreases → PO2 does not have to drop as low to trigger oxygen release, occurs when tissues need more oxygen)

a. ) shift to the left
b. ) shift to the right

A

shift to the left

A shift to the left occurs in conditions that favor oxygen release.

Hgb affinity for oxygen decreases

PO2 does not have to drop as low to trigger oxygen release, occurs when tissues need more oxygen

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16
Q

Hypoxia / Hypercapnia

General criteria:

When PO2 < 50 mm Hg, PCO2 > 50 mm Hg, or both

Generally want PO2 > 80-90 and PCO2 < 35-45

A
17
Q

Regulation / Control of Breathing through nervous system

Controls the diameter of airways.

a. ) Respiratory Center
b. ) Autonomic Nervous System

A

Autonomic Nervous System

Controls the diameter of airways.

Two Components of ANS:

  1. ) Sympathetic Stimulation (fight or flight / bronchodilation)
  2. ) Parasympathetic Stimulation (bronchoconstriction)
18
Q

Regulation / Control of Breathing through nervous system

Provides continuous input to muscles that control respiration.

a. ) Respiratory Center
b. ) Autonomic Nervous System

A

Respiratory Center

Provides continuous input to muscles that control respiration.

Located in pons and medulla.

Main control center

Two components of Respiratory Center:

  1. ) Automatic Regulation - chemoreceptors & lung receptors
  2. ) Volutary Regulation
19
Q

Regulation / Control of Breathing through nervous system

The respiratory center is located in the pons and medulla (brain stem). Automatic regulation is controlled by chemoreceptors and lung receptors. ______ monitor blood levels of oxygen, carbon dioxide, and pH.

a. ) chemoreceptors
b. ) lung receptors

A

Chemoreceptors

monitor blood levels of oxygen, carbon dioxide, and pH.

20
Q

Regulation / Control of Breathing through nervous system

The respiratory center is located in the pons and medulla (brain stem). Automatic regulation is controlled by chemoreceptors and lung receptors. ______ monitor changes in airway pressure/stretch, lung inflation, lung congestion, etc.

a. ) chemoreceptors
b. ) lung receptors

A

Lung Receptors

monitor changes in airway pressure/stretch, lung inflation, lung congestion, etc.