Packet 4 - immunity & inflammation Flashcards
Found on cell membrane of B lymphocytes.
a. ) IgG
b. ) IgA
c. ) IgM
d. ) IgD
e. ) IgE
d.) IgD
What are the two primary lymphoid organs?
Bone marrow & thymus
Adaptive immunity (specific/acquired)
Upon subsequent exposure to an antigen → stimulates production of plasma cells.
a. ) CD4+ or Helper T cells (TH)
b. ) CD8+ or Cytotoxic T cells (TC or CTLs)
c. ) Suppressor T cells (Regulatory T cells)
d. ) Memory cells
e. ) plasma cells
d.) Memory cells
innate immunity (natural/native/nonspecific)
Cause lysis of many different kinds of cells (both body cells and pathogens).
a. ) phagocytic WBCs
b. ) natural killer (NK) cells
c. ) skin and mucous membranes
d. ) cytokines
e. ) complement system
e.) complement system
innate immunity (natural/native/nonspecific)
Induces fever by acting on the hypothalamic thermoregulatory center to increase the set point (makes WBCs more active).
a. ) phagocytic WBCs
b. ) natural killer (NK) cells
c. ) skin and mucous membranes
d. ) cytokines
e. ) complement system
d.) cytokines
Presence usually suggests a current infection by the pathogen.
a. ) IgG
b. ) IgA
c. ) IgM
d. ) IgD
e. ) IgE
c.) IgM
innate immunity (natural/native/nonspecific)
Consists of a “cascade” of about 20 plasma proteins that, when activated, enhances inflammation and WBC efficiency.
a. ) phagocytic WBCs
b. ) natural killer (NK) cells
c. ) skin and mucous membranes
d. ) cytokines
e. ) complement system
e.) complement system
Adaptive immunity (specific/acquired)
Kill tumor cells and virus-infected cells by similar mechanisms to NK cells, except for the fact that they need to be activated and look for specific cells to attack.
a. ) CD4+ or Helper T cells (TH)
b. ) CD8+ or Cytotoxic T cells (TC or CTLs)
c. ) Suppressor T cells (Regulatory T cells)
d. ) Memory cells
e. ) plasma cells
b.) CD8+ or Cytotoxic T cells (TC or CTLs)
Adaptive immunity (specific/acquired)
Secrete antibodies/immunoglobulins which bind to and aggregate antigens to aid in their removal by phagocytes.
a. ) CD4+ or Helper T cells (TH)
b. ) CD8+ or Cytotoxic T cells (TC or CTLs)
c. ) Suppressor T cells (Regulatory T cells)
d. ) Memory cells
e. ) plasma cells
e.) plasma cells
innate immunity (natural/native/nonspecific)
Assist in processing antigens, serving as antigen-presenting cells (APCs) to T lymphocytes → activates adaptive immune response.
a. ) phagocytic WBCs
b. ) natural killer (NK) cells
c. ) skin and mucous membranes
d. ) cytokines
e. ) complement system
a.) phagocytic WBCs
Adaptive immunity (specific/acquired)
Suppresses activity of self-reactive immune cells, preventing immune activity against self-cells.
a. ) CD4+ or Helper T cells (TH)
b. ) CD8+ or Cytotoxic T cells (TC or CTLs)
c. ) Suppressor T cells (Regulatory T cells)
d. ) Memory cells
e. ) plasma cells
c.) Suppressor T cells (Regulatory T cells)
Main Ig in body secretions. Protects mucous membranes (tears, saliva, GI secretions, breast milk).
a. ) IgG
b. ) IgA
c. ) IgM
d. ) IgD
e. ) IgE
b.) IgA
innate immunity (natural/native/nonspecific)
Small, hormone-like proteins that act primarily on immune cells, function to regulate immune response (ex: interferons, interleukins, tumor necrosis factor, colony-stimulating factors).
a. ) phagocytic WBCs
b. ) natural killer (NK) cells
c. ) skin and mucous membranes
d. ) cytokines
e. ) complement system
d.) cytokines
Found on cell membrane of B lymphocytes. When it binds with an antigen, it stimulates B cells to produce other specific Ig.
a. ) IgG
b. ) IgA
c. ) IgM
d. ) IgD
e. ) IgE
d.) IgD
Adaptive immunity (specific/acquired)
Regulate and enhance the response of other T and B cells. Activated by recognition of antigens presented by APCs → secrete cytokines that activate many other cells of immune system (master switch).
a. ) CD4+ or Helper T cells (TH)
b. ) CD8+ or Cytotoxic T cells (TC or CTLs)
c. ) Suppressor T cells (Regulatory T cells)
d. ) Memory cells
e. ) plasma cells
a.) CD4+ or Helper T cells (TH)
Involved in allergic reactions and parasitic infections.
a. ) IgG
b. ) IgA
c. ) IgM
d. ) IgD
e. ) IgE
e.) IgE
innate immunity (natural/native/nonspecific)
Enhances chemotaxis.
a. ) phagocytic WBCs
b. ) natural killer (NK) cells
c. ) skin and mucous membranes
d. ) cytokines
e. ) complement system
e.) complement system
innate immunity (natural/native/nonspecific)
Regulates the inflammatory response.
a. ) phagocytic WBCs
b. ) natural killer (NK) cells
c. ) skin and mucous membranes
d. ) cytokines
e. ) complement system
d.) cytokines
innate immunity (natural/native/nonspecific)
Can trigger degranulation of mast cells, causing the release of histamine and other inflammatory mediators.
a. ) phagocytic WBCs
b. ) natural killer (NK) cells
c. ) skin and mucous membranes
d. ) cytokines
e. ) complement system
e.) complement system
Adaptive immunity (specific/acquired)
Stops the immune response once foreign/harmful agent is destroyed.
a. ) CD4+ or Helper T cells (TH)
b. ) CD8+ or Cytotoxic T cells (TC or CTLs)
c. ) Suppressor T cells (Regulatory T cells)
d. ) Memory cells
e. ) plasma cells
c.) Suppressor T cells (Regulatory T cells)
innate immunity (natural/native/nonspecific)
Causes opsonization (the coating of antigen-antibody complexes so they can be engulfed and cleared more efficiently by phagocytes.
a. ) phagocytic WBCs
b. ) natural killer (NK) cells
c. ) skin and mucous membranes
d. ) cytokines
e. ) complement system
e.) complement system
innate immunity (natural/native/nonspecific)
These cells activate the adaptive immune response.
a. ) phagocytic WBCs
b. ) natural killer (NK) cells
c. ) skin and mucous membranes
d. ) cytokines
e. ) complement system
a.) phagocytic WBCs
The first to appear in response to an antigen. Its presence usually suggests a current infection by the pathogen. Does not stay elevated for long.
a. ) IgG
b. ) IgA
c. ) IgM
d. ) IgD
e. ) IgE
c.) IgM
innate immunity (natural/native/nonspecific)
Neutrophils and monocytes/macrophages.
a. ) phagocytic WBCs
b. ) natural killer (NK) cells
c. ) skin and mucous membranes
d. ) cytokines
e. ) complement system
a.) phagocytic WBCs
Adaptive immunity (specific/acquired)
Believed to be subset of CD4+ or CD8+ T cell.
a. ) CD4+ or Helper T cells (TH)
b. ) CD8+ or Cytotoxic T cells (TC or CTLs)
c. ) Suppressor T cells (Regulatory T cells)
d. ) Memory cells
e. ) plasma cells
c.) Suppressor T cells (Regulatory T cells)
innate immunity (natural/native/nonspecific)
Influences production, maturation, and activity of almost all inflammatory and immune cells.
a. ) phagocytic WBCs
b. ) natural killer (NK) cells
c. ) skin and mucous membranes
d. ) cytokines
e. ) complement system
d.) cytokines
innate immunity (natural/native/nonspecific)
Programmed to automatically kill tumor cells and virus-infected cells, by releasing toxic substances, such as cytolytic enzymes, toxic cytokines, etc.
a. ) phagocytic WBCs
b. ) natural killer (NK) cells
c. ) skin and mucous membranes
d. ) cytokines
e. ) complement system
b.) natural killer (NK) cells
Crosses the placenta. Provides protection for newborns for first few months (stays active in the blood for a long time).
a. ) IgG
b. ) IgA
c. ) IgM
d. ) IgD
e. ) IgE
a.) IgG
Adaptive immunity (specific/acquired)
Remain in the body for a long time, enable more rapid response on repeat exposure (recognizes the antigen and stimulates T cell activity).
a. ) CD4+ or Helper T cells (TH)
b. ) CD8+ or Cytotoxic T cells (TC or CTLs)
c. ) Suppressor T cells (Regulatory T cells)
d. ) Memory cells
e. ) plasma cells
d.) Memory cells
