Oxytocin/ Pitocin/ Syntocinon

Question 1

Oxytocin Class

Answer 1

• Hormone

* Uterine Stimulant

Question 2

Oxytocin Action

Answer 2

• Secreted by the posterior pituitary gland.
• Causes rhythmic contraction of uterine smooth muscle.
• Decreases postpartum hemorrhage.
• Stimulates the mammary glands to increase
lactation but does not increase milk production.

Question 3

Oxytocin Indications

Answer 3

Prehospital–excessive postpartum hemorrhage

Question 4

Oxytocin Contraindications

Answer 4

Before administration it is essential to verify that the baby and placenta have been delivered and there is not an additional fetus in the uterus.

Question 5

Oxytocin Precautions

Answer 5

• Over stimulation of the uterus and possible rupture, monitor vital signs and uterine tone.
• HTN
• Cardiac Arrhythmias

Question 6

Oxytocin Dosage

Answer 6

Adults: (Medical Control Order)
• IV—10 U in 250 ml of NS administered at a rate to control uterine contractions.
• Infused 10u/250 ml over 5 to 10 minutes; repeat if needed and continue fundal massage.
• IM–3-10 units.
Peds:
Not given to peds

Question 7

Oxytocin Onset/ Duration

Answer 7

• Onset: IV—Immediate. IM—3-5 minutes

* Duration: IV—1 hour after infusion is stopped. IM—2-3 hours

Question 8

Oxytocin Side Effects

Answer 8

• Hypertension or Hypotension
• Dysrhythmias
• Angina
• Anaphylaxis
• Fluid retention
• Pelvic hematoma
• Uterine spasm/rupture
• N/V

Question 9

Oxytocin Interactions

Answer 9

Other vasopressors may potentiate hypertension.