Dopamine, Intropin Flashcards
1
Q
Dopamine Class
A
- Adrenergic Dopaminergic Catecholamine
* Sympathomimetic
2
Q
Dopamine Action
A
- Precursor of norepinephrine.
- 1-2 µg/kg/min–dopaminergic receptors–dilation of renal, mesenteric, and cerebral arteries.
- 2-10 µg/kg/min–beta receptors–inotropic, chronotropic
- 10-20 µg/kg/min–alpha and beta–vasoconstriction of renal, mesenteric, and peripheral arteries and veins
- > 20 µg/kg/min–Mimics pure alpha effects similar, to norepinepherine like effects. It is occasionally used at this range in-hospital.
3
Q
Dopamine Indication
A
- Cardiogenic Shock
- Cardiogenic Shock w/ Pulmonary Edema (CHF)
- Hypovolemic Shock/ Hypotension (after fluid resuscitation)
- Neurogenic Shock
- Septic Shock
4
Q
Dopamine Contraindication
A
- Women on oxytocin
- Tachydysrhythmias
- VF/VT
- Uncorrected hypovolemia
- Patients with known pheochromocytoma
5
Q
Dopamine Precaution
A
- MAOIs, TCAs, other cardiac stimulants, vasopressors, will cause increased HR, and SV dysrhythmias
- Will precipitate in basic, alkaline solutions
- May cause necrosis, sloughing at infusion site
- Pregnancy (C)
6
Q
Dopamine Dosage
A
Adults:
2-20 µg/kg/min, up to 50 µg/kg/min w/ medical control guidance. Titrated to effect, run through a large vein.
Generally add two vials 200 mg to 250 ml NS, yielding 1600 µg/ml
Pediatrics:
2-20 µg/kg/min, with 10 µg/kg/min is a reasonable starting dose, titrated to effect, generally not exceeding 20 µg/kg/min. Add 6 mg x weight in kg diluted to 100 ml, to create drip. 1gtt/min (ml/hr) equals 1 µg/kg/min.
7
Q
Dopamine Onset/Duration
A
- Onset: 2-4 min.
* Duration: 10-15 min
8
Q
Dopamine Side Effects
A
- Dysrhythmias
- HTN
- Headache
- N/V
- Dizziness
- Tremors
- Tachycardia(VT/VF)
- Flushing
- Angina, AMI
- Pain
- Ectopy
- Bradycardia
9
Q
Dopamine Interactions
A
- Potentiating effects–TCAs, MAOIs, bretylium
- Precipitates in Alkaline Solutions
- Dopamine may cause hypotension when used concomitantly with phenytoin (Dilantin)
