Ketamine, Ketanest, Ketaset, Ketalar

Question 1

Ketamine Class

Answer 1

• Dissociative anesthetic

* NMDA receptor antagonist

Question 2

Ketamine Action

Answer 2

Produces dissociative analgesia and sedation.

Question 3

Ketamine Indications

Answer 3

For use in medication assisted intubation in conjunction with a paralytic

Question 4

Ketamine Contraindications

Answer 4

• Most contraindications are related to the release of catecholamines increasing hypertension and tachycardia.
o Hypertensive Crisis
o Under the influence of methamphetamine or other similar drug
• Acute globe injury or glaucoma
o Increased intraocular pressure
• When significant elevations in BP might prove harmful:
o Aortic dissection
o Acute Myocardial Infarction, angina
o Intracranial hemorrhage
• Schizophrenia
o Increases psychosis
• Consider use of versed in above contraindications

Question 5

Ketamine Precautions

Answer 5

be cautious with situations in contraindications tab

Question 6

Ketamine Dosage

Answer 6

Adults/Peds:

• 2mg/kg SIVP one minute prior to paralytic administration

Question 7

Ketamine Onset/ Duration

Answer 7

• Onset: 45-60 seconds. (Give paralytic post onset)

* Duration: 5-15 minutes IV

Question 8

Ketamine Side Effects

Answer 8

• Vivid Dreams
• Hallucinations
• Delirium
• Recovery Agitation
• Tachycardia
• Hypertension
• Dysphoria
• Hypersalivation
• N/V
• Anaphylaxis
• Reemergence phenomenon
• Arrhythmias
• CNS Depression
• Respiratory Depression

Question 9

Ketamine Interactions

Answer 9

Additive/Potentiation Effects:
• Any medication that stimulates catecholamine release will result in hypertension, tachycardia and arrhythmias
• Benzodiazepines increase respiratory and CNS depression
• Opiates will increase respiratory and CNS depression
• Sedative hypnotics will increase respiratory and CNS depression