Osteoporosis Flashcards

1
Q

What is the most common disorder of calcium metabolism?

A

Osteoporosis

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2
Q

What are the three primary preventions of osteoporosis?

A

Calcium
Vitamin D
Lifestyle

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3
Q

What is the use of Calcitonin-Salmon?

A

Used in the treatment, not prevention, of osteoporosis

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4
Q

What is the MOA of Calcitonin-Salmon?

A

Mimics calcitonin by inhibiting osteoclast activity and promoting renal excretion or calcium

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5
Q

What class of drug is Alendronate?

A

Bisphosphonate

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6
Q

You can use Alendronates regardless of what?

A

Gender

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7
Q

What is the MOA of Alendronate?

A

Suppresses bone resorption by decreasing osteoclast activity

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8
Q

What is the appropriate dosing for Alendronate?

A

AM on an empty stomach

Sit up right for 30 mins

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9
Q

What are the adverse effects of Alendronate?

A

Esophagitis

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10
Q

What do you assess for before administering Alendronate?

A

History of Pregnancy

Any disorder that can impede swallowing

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11
Q

What drug class does Evista (Raloxifene) belong to?

A

Selective Estrogen Receptor Modulator (SERM)

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12
Q

What is Raloxifene used for?

A

Osteoporosis; preserves Bone Mass Density; reduces spinal fractures by 55%

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13
Q

What is the MOA of Raloxifene?

A

Structurally similar to estrogen

Can behave as an agonist or antagonist

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14
Q

What are some adverse effects of Raloxifene?

A

May increase her flashes
Leg cramps
Thromboembolic events

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15
Q

What do you want to assess for before administering Raloxifene?

A

History of Pregnancy

history of VTE

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16
Q

What interventions and evaluations should you expect with Raloxifene?

A

If client will experience prolonged immobility, medication should be stopped 72 hours prior
S/S of difficulty breathing, weakness on one side of the body, pain, warmth, swelling in extremities

17
Q

What does Forteo do?

A

First and only drug that works by increasing bone formation

18
Q

What does Denosumab do?

A

RANKL inhibitor

19
Q

What is a side effects of Denosumab?

A

Osteonecrosis of the jaw