Beta-Adrenergic Antagonists

Question 1

What are some major consequences of blocking Beta?

Answer 1

Reduced heart rate
Reduced force of contraction
Reduced velocity

Question 2

Name a first generation beta blocker

Answer 2

Propranolol

Question 3

What does Propranolol do?

Answer 3

Block beta1 and beta2 receptors

Question 4

Name a second generation drug

Answer 4

Metoprolol

Question 5

What does Metoprolol do?

Answer 5

Produce selective blockade of beta1 receptors

Question 6

What is the use of beta blockers?

Answer 6

Hypertension
Angina pectoris
Cardiac dysrhythmias

Question 7

What is the MOA of Beta Blockers?

Answer 7

Blockade of Beta1 receptors in the heart

Blockade of Beta2 receptors on arterioles loved in the heart, lungs, and skeletal muscle

Question 8

What are some adverse reactions of beta blockers?

Answer 8

Bradycardia

Inhibition of glycogenolysis (propranolol)

Question 9

What is propanolol usually given for?

Answer 9

Anxiety

Question 10

What should you assess before you administer a beta blocker?

Answer 10

HR and BP
Orphan CCB and insulin 
*Orphan CCB never taking together with a beta blocker 
Sinus Bradycardia - hard stop
Anything bigger than a 1st AV block

Question 11

What should you educate a patient before administering beta blockers?

Answer 11

Do not abruptly stop to avoid rebound cardiac excitation