Opioids Analgesics Flashcards

1
Q

What is a pure opioid agonist?

A

Morphine

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2
Q

What is the Nonopioid Centrally Acting Analgesics?

A

Tramadol

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3
Q

What is the pure Opioid Antagonist?

A

Naloxone

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4
Q

What is the MOA for morphine?

A

Mimics the actions of endogenous opioid peptides

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5
Q

What are the pharmacokinetics for morphine?

A

IV doses &laquo_space;Oral due to 1st pass effect

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6
Q

What are the serious adverse effects of morphine?

A

Respiratory distress

Overdose

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7
Q

What are the common adverse effects of morphine?

A

Constipation
Urinary retention
Nausea

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8
Q

What do you want to check for upon pre-adminstration of morphine?

A

Respiratory Rate
Mental Status
Blood Pressure

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9
Q

How slow should you inject morphine?

A

over 4-5 minutes

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10
Q

What is the key education for morphine?

A

Fall risks
limit hazardous activity due to drowsiness
Increase fluid, fiber, and activity to limit constipation
Cough at regular intervals

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11
Q

What scale do you want to use to assess sedation?

A

Richmond Agitation and Sedation Scale (RASS)

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12
Q

What is the classic triad for an opioid overdose?

A

Coma
Respiratory depression
Pinpoint pupils

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13
Q

What is considered the ‘antidote’ for an opioid overdose?

A

Naloxone (Narcan)

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14
Q

What is the MOA of Tramadol

A

Blocks uptake of norepinephrine & serotonin

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15
Q

What are the adverse effects of Tramadol?

A
Sedation
Dizziness
Headache
Dry Mouth 
Constipation
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16
Q

What is a serious adverse effect of Tramadol?

A

It can be used as a suicide vehicle

17
Q

What should you check in the MAR before administering Tramadol?

A

CNS depressants

Antidepressants

18
Q

What is the key patient education for Tramadol?

A

Fall Risks