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Pharm Test 1 > Calcium Channel Blockers > Flashcards

Calcium Channel Blockers Flashcards

1
Q

What kind of muscle are Calcium Channel Blockers used for?

A

Smooth Muscle

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2
Q

What are agents that affect the heart and blood vessels called?

A

Orphan CCB

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3
Q

What are agents that act mainly on blood vessels called?

A

Dihydropyridines

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4
Q

What are the two Orphan CCB called?

A

Verapamil

Diltiazem

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5
Q

What is the Dihydropyridine called?

A

Nifedipine

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6
Q

What are Orphan CCB used for?

A

Angine Pectoris
Essential HTN
Cardiac dysrhythmias

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7
Q

What is the MOA of Orphan CCB?

A

Dilation of peripheral arterioles lower after-load

Decrease HR, AV conduction, force of contraction

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8
Q

What are the adverse effects of CCB?

A 
Constipation
Dizziness
Facial flushing
Edema
Worsening Cardiac dysfunction
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9
Q

What is a drug/drug interaction with Orphan CCB?

A

Digoxin

Beta Blockers

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10
Q

What do you want to assess before administering Orphan CCB’s?

A

HR
BP
Chest Pain History

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11
Q

What do you want to evaluate after you administer Orphan CCB’s?

A

Assess for over-shooting

Monitor for increased peripheral edema

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12
Q

What is the use of Nifedipine?

A

Angina pectoris

Essential HTN

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13
Q

What is the MOA if Nifedipine?

A

Dilation of peripheral arterioles lower afterload

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14
Q

What are the two different dosing for Nifedipine?

A

Sustained Release

Immediate Release

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15
Q

What are the adverse effects of Nifedipine?

A 
Dizziness
Facial flushing
Edema
Reflex tachycardia
Toxicity
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16
Q

What is a drug interaction for Nifedipine?

A

Digoxin

17
Q

What do you assess before administering Nifedipine?

A

HR
BP
Chest Pain History
Renal and liver function (drug gets metabolized by liver)

18
Q

What do you want to evaluate after administering Nifedipine?

A

Severe hypotension and cardiotoxicity

19
Q

What does the selective dilation of arterioles do?

A

Decreases afterload

20
Q

What does the selective dilation of veins do?

A

Decreases preload

21
Q

What are the adverse effects related to vasodilation?

A

Postural hypotension
Reflex tachycardia
Expansion of blood volume

22
Q

What is the use of Nitroglycerin?

A

Reduction of frequency and intensity of angina attacks

23
Q

What is something to know when it comes to dosing of Nitroglycerin?

A

Continuous use of Nitro can produce tolerance within 24 hours

24
Q

What are some adverse effects of Nitro?

A

Headache
Orthostatic hypotension
Reflex tachycardia

25
Q

What do you want to check in the MAR before administering Nitro?

A

PDE5 inhibitor

Pharm Test 1 (15 decks)

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