Gout Drugs

Question 1

What is Colchicine primary used for?

Answer 1

Acute goaty arthritis

Question 2

What is the MOA of Colchicine?

Answer 2

Unknown

Question 3

What are the adverse effects of Colchicine?

Answer 3

GI Upset
Suppress bone marrow
Rhabdo

Question 4

What assessments should you do before administering Colchicine?

Answer 4

CDC

Renal and hepatic function tests

Question 5

What should you avoid taking with Colchicine?

Answer 5

Grapefruit juice

Question 6

What is allopurinol used for?

Answer 6

Chronic top gout, reverses existing gout

Question 7

What is the MOA for Allopurinol?

Answer 7

Reduce blood uric acid levels by preventing goat to form

Question 8

What are the adverse effects of allopurinol?

Answer 8

Can cause an acute attack

Question 9

What is the use of Probenecid?

Answer 9

Prevents and decreases tophi

Question 10

What is the MOA of Probenecid?

Answer 10

Promotes renal uric acid excretion through tubular resabsorbtion of uric acid

Question 11

What are the adverse effects of Probenecid?

Answer 11

Renal injury

Question 12

What should you assess for before administering Probenecid?

Answer 12

Acute gout flare up

Question 13

When should you stop Allopurinol immediately?

Answer 13

If a rash develops