Opioid Analgesics Flashcards by Jhaunte Braithwaite

Q

What is the mechanism of action of opioid analgesics?

A

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Q

What are the opioid receptor types ?

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Q

What are the relations of physiological effects to receptor type?

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Q

What are the cellular actions of opioids?

A

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Q

What are the neural mechanisms of analgesia?

A

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Q

What is spinal analgesia?

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Q

How can opioids affect spinal analgesia?

A

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Q

What are the classifications of opioid analgesics?

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Q

Describe morphine as an opioid agonist

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Q

Describe fentanyl as an opioid analgesic

A

Agonist to u, that’s it

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Q

Describe Meperidine as an opioid analgesic

A

Agonist to u, that’s it

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Q

Describe Methadone as an opioid analgesic

A

Agonist to u, that’s it

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Q

Describe Codeine as an opioid analgesic

A

Weak agonist to u, weak agonist to delta

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Q

Describe Pentazocine as an opioid analgesic

A

Antagonist to u, agonist to k

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Q

Describe Butorphanol as an opioid analgesic

A

Antagonist to u, agonist to

K

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Q

Describe Nalbuphine as an opioid analgesic

A

Antagonist to u, agonist to

K

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Q

Describe Buprenorphine as an opioid analgesic

A

Weak agonist- u, antagonist to k

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Q

What are the opioid analgesics antagonists?

A

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Q

What are the CNS effects of opioid analgesics ?

A

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Q

What are the peripheral effects of opioid analgesics?

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Q

Summarize how opioids metabolized

A

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Q

What is morphine conjugated to?

A

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Q

How is heroin metabolized?

A

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Q

How are codeine, oxycodone and hydrocodone metabolized?

A

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How can meperidine cause seizures?

How are opioids excreted?

What are the uses of the opioid analgesics?

What are the adverse effects of opioid analgesics?

What causes medical tolerance and dependence?A

What are the use of pure agonists with weak partial agonists?

How do we treat patients with head injuries?

What are the contraindications with impaired pulmonary function?

What are the contraindications with impaired hepatic function?

What are the contraindications with impaired renal function?

What are the contraindications with pregnancy?

What are the contraindications for children & breastfeeding mothers?

What are sedative-hypnotics?

What are MAO inhibitor drug interactions?

What are the properties of specific agents?

What are the agonists?

What are the functions of morphine, hydrmorphine & oxymorohone?

What is the drug of choice for severe pain?

Morphine

What are the characteristics of heroin?

What are the characteristics of meperidine?

What are the characteristics of fentanyl?

What are the characteristics of methadone?

What are the users of methadone ?

What are the adverse effects of methadone?

What is the characteristics of levorphanol?

What is oxycodone?

What is hydrocodone?

What is codeine?

What are the mixed-agonists-antagonists?

What’s the purpose of pentazocine, butorphanol, nalbuphine & buprenorphine?

What is the ceiling effect and sychomimetic effect of

What is tramdol?

What are the opioid antagonists?

What are the efficacy of opioids?

What are the antitussives?

What are the anti motility agents?

What are the anti motility agents?

Describe diphenoxylate

What is Loperamide?