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Principals To Clinical Medicine > Opioid Analgesics > Flashcards

Opioid Analgesics Flashcards

1
Q

What is the mechanism of action of opioid analgesics?

A
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2
Q

What are the opioid receptor types ?

A
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3
Q

What are the relations of physiological effects to receptor type?

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4
Q

What are the cellular actions of opioids?

A
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5
Q

What are the neural mechanisms of analgesia?

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6
Q

What is spinal analgesia?

A
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7
Q

How can opioids affect spinal analgesia?

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8
Q

What are the classifications of opioid analgesics?

A
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9
Q

Describe morphine as an opioid agonist

A
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10
Q

Describe fentanyl as an opioid analgesic

A

Agonist to u, that’s it

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11
Q

Describe Meperidine as an opioid analgesic

A

Agonist to u, that’s it

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12
Q

Describe Methadone as an opioid analgesic

A

Agonist to u, that’s it

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13
Q

Describe Codeine as an opioid analgesic

A

Weak agonist to u, weak agonist to delta

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14
Q

Describe Pentazocine as an opioid analgesic

A

Antagonist to u, agonist to k

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15
Q

Describe Butorphanol as an opioid analgesic

A

Antagonist to u, agonist to

K

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16
Q

Describe Nalbuphine as an opioid analgesic

A

Antagonist to u, agonist to

K

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17
Q

Describe Buprenorphine as an opioid analgesic

A

Weak agonist- u, antagonist to k

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18
Q

What are the opioid analgesics antagonists?

A
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19
Q

What are the CNS effects of opioid analgesics ?

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20
Q

What are the peripheral effects of opioid analgesics?

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21
Q

Summarize how opioids metabolized

A
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22
Q

What is morphine conjugated to?

A
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23
Q

How is heroin metabolized?

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24
Q

How are codeine, oxycodone and hydrocodone metabolized?

A
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25
Q

How can meperidine cause seizures?

A
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26
Q

How are opioids excreted?

A
27
Q

What are the uses of the opioid analgesics?

A
28
Q

What are the adverse effects of opioid analgesics?

A
29
Q

What causes medical tolerance and dependence?A

A
30
Q

What are the use of pure agonists with weak partial agonists?

A
31
Q

How do we treat patients with head injuries?

A
32
Q

What are the contraindications with impaired pulmonary function?

A
33
Q

What are the contraindications with impaired hepatic function?

A
34
Q

What are the contraindications with impaired renal function?

A
35
Q

What are the contraindications with pregnancy?

A
36
Q

What are the contraindications for children & breastfeeding mothers?

A
37
Q

What are sedative-hypnotics?

A
38
Q

What are MAO inhibitor drug interactions?

A
39
Q

What are the properties of specific agents?

A
40
Q

What are the agonists?

A
41
Q

What are the functions of morphine, hydrmorphine & oxymorohone?

A
42
Q

What is the drug of choice for severe pain?

A

Morphine

43
Q

What are the characteristics of heroin?

A
44
Q

What are the characteristics of meperidine?

A
45
Q

What are the characteristics of fentanyl?

A
46
Q

What are the characteristics of methadone?

A
47
Q

What are the users of methadone ?

A
48
Q

What are the adverse effects of methadone?

A
49
Q

What is the characteristics of levorphanol?

A
50
Q

What is oxycodone?

A
51
Q

What is hydrocodone?

A
52
Q

What is codeine?

A
53
Q

What are the mixed-agonists-antagonists?

A
54
Q

What’s the purpose of pentazocine, butorphanol, nalbuphine & buprenorphine?

A
55
Q

What is the ceiling effect and sychomimetic effect of

A
56
Q

What is tramdol?

A
57
Q

What are the opioid antagonists?

A
58
Q

What are the efficacy of opioids?

A
59
Q

What are the antitussives?

A
60
Q

What are the anti motility agents?

A
61
Q

What are the anti motility agents?

A
62
Q

Describe diphenoxylate

A
63
Q

What is Loperamide?

A

Principals To Clinical Medicine (50 decks)

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