Amyloidosis & Pigmentation Flashcards
What is Amyloidosis?
What is amyloid?
Where does amyloid c9me from?
What is the morphology of amyloid?
What are the classifications of Amyloidosis?
Describe systemic Amyloidosis
Describe localized Amyloidosis
Describe hereditary Amyloidosis
Describe the gross appearance of Amyloidosis?
Describe the microscopic features of Amyloidosis
What does Amyloidosis look like?
Describe Amyloidosis of kidney
Describe Amyloidosis of spleen
Describe Amyloidosis of the liver
Describe Amyloidosis of heart
Discuss the symptoms & pathology of the kidney
Discuss the symptoms & pathology of the heart Amyloidosis
Discuss the symptoms & pathology of the liver Amyloidosis
Discuss the symptoms & pathology of the spleen Amyloidosis
Discuss the symptoms & pathology of the vascular Amyloidosis
Discuss the symptoms & pathology of the peripheral nerves Amyloidosis
Discuss the symptoms & pathology of the coagulation Amyloidosis
Discuss the symptoms & pathology of the join t Amyloidosis
What organs are not as commonly affected with Amyloidosis?
What is the diagnosis of Amyloidosis?
What are the intracellular accumulations?
Contrast endogenous, exogenous accumulations
What are the mechanisms of accumulation ?
What are examples of exogenous pigments?
What is lipofuscin?
What is bile?
What is hemosiderin?
What is the etiology of gout and gouty arthritis?
What is the pathogenesis of gout & gouty arthritis?
What is the epidemiology of gout and gouty arthritis?
What are the risk factors of gout and gouty arthritis ?
What are the classifications of primary and secondary gout?
Describe the morphology of gout
Describe diagnosis of gout
What are the Clinical features of gout?
What are the main endogenous pigments?
What are the main exogenous pigments?
Patient with plasma cell dyscrasias such as multiple myeloma. What type of Amyloid?
AL
Chronic inflammatory conditions like rheumatoid arthritis, chronic osteomyelitis ; bronchiectasis; inflammatory bowel disease. What type of Amyloid?
AA
Chronic renal failure associated with hemodialysis. What type of Amyloid?
What type of Amyloid is present in old age? (Systemic senile Amyloidosis)
ATTR (Transthyretin)
What are the types f amyloid is Ahlzeimer’s?
AB (amyloid beta protein)
What type of Amyloid is in medullary carcinoma thyroid?
Acal (calcitonin)
What type of Amyloid is in familial amyloidotic polyneuropathy?
ATTR (Transthyretin)