Autacoids Flashcards

1
Q

What are autacoids?

A
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2
Q

What are the mechanisms of action of histamine?

A
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3
Q

How do H1 receptors work?

A
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4
Q

How do H2 receptors work?

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5
Q

How does histamine affect vasodilation?

A
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6
Q

How does the heart depend on H2 receptors?

A
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7
Q

How do histaminevreceptors increase capillary permeability?

A
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8
Q

How does histamine affect extra vascular smooth muscle?

A
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9
Q

How does the nervous system depend on histamine receptors?

A
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10
Q

How does secretory tissue depend on Histamine receptors ?

A
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11
Q

What is the role of histamine in anaphylaxis?

A
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12
Q

What are the uses of histamine?

A
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13
Q

What are the antagonists of histamine ?

A
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14
Q

What are physiological antagonists?

A
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15
Q

What are histamine antagonists?

A
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16
Q

What are the histamine receptor antagonists?

A

H1 receptor antagonists

H2 receptor antagonists

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17
Q

What are H1 receptor antagonists?

A
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18
Q

What are the examples of H1 receptor antagonists ?

A
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19
Q

What are the second generation H1 receptor antagonists?

A
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20
Q

What are the actions of H1 receptor antagonists ?

A
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21
Q

How can H anatagonists be used for allergic conditions?

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22
Q

What are the uses of H antagonists for treating motion sickness & nausea?

A
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23
Q

What are somnifacients?

A
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24
Q

What are the adverse effects of H1 receptor antagonists?

A
25
Q

What are the H2 receptor antagonists?

A
26
Q

What are the uses of H2 receptor antagonists?

A
27
Q

What are the adverse effects of H2 receptor antagonists?

A
28
Q

What is the mechanism of action of serotonin?

A
29
Q

What are the serotonin agonists

A
30
Q

What are 5-HT1D/1B receptor agonists?

A
31
Q

What is metoclopramide?

A
32
Q

What is cisapride?

A
33
Q

What are serotonin antagonists?

A
34
Q

What is cyproheptadine?

A
35
Q

What is Ondansetron?

A
36
Q

What are ergot alkaloids?

A
37
Q

What is the mechanism of action of ergot alkaloids?

A
38
Q

How do we treat migraines?

A
39
Q

How do we treat hyperprolactinemia?

A
40
Q

How do we treat postpartum hemorrhage?

A
41
Q

How do we diagnose variant angina?

A
42
Q

What are the adverse effects of ergot alkaloids?

A
43
Q

What are the main subgroups of eicosanoids?

A
44
Q

What are the main source of eicosanoid?

A
45
Q

Where is arachidonic acid be found?

A
46
Q

Where are the 2 major pathways of eicosanoid synthesis?

A
47
Q

What is the COX pathway?

A
48
Q

What is Lipoxygenase pathway?

A
49
Q

What are the mechanisms of action of eicosanoids?

A
50
Q

What are the uses of eicosanoid- misoprostol?

A
51
Q

What is dinoprostone?

A
52
Q

What is Alprostadil?

A
53
Q

What is epoprostenol?

A
54
Q

What is latanoprostol?

A
55
Q

What are the types of eicosanoid antagonists?

A
56
Q

What are the leukotrienes pathway inhibitors?

A
57
Q

How do glucocorticoids of inhibiting leukotrienes synthesis ?

A
58
Q

How do NSAIDs inhibit leukotrienes pathway synthesis?

A