Autacoids Flashcards

1
Q

What are autacoids?

A
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2
Q

What are the mechanisms of action of histamine?

A
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3
Q

How do H1 receptors work?

A
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4
Q

How do H2 receptors work?

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5
Q

How does histamine affect vasodilation?

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6
Q

How does the heart depend on H2 receptors?

A
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7
Q

How do histaminevreceptors increase capillary permeability?

A
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8
Q

How does histamine affect extra vascular smooth muscle?

A
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9
Q

How does the nervous system depend on histamine receptors?

A
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10
Q

How does secretory tissue depend on Histamine receptors ?

A
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11
Q

What is the role of histamine in anaphylaxis?

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12
Q

What are the uses of histamine?

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13
Q

What are the antagonists of histamine ?

A
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14
Q

What are physiological antagonists?

A
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15
Q

What are histamine antagonists?

A
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16
Q

What are the histamine receptor antagonists?

A

H1 receptor antagonists

H2 receptor antagonists

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17
Q

What are H1 receptor antagonists?

A
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18
Q

What are the examples of H1 receptor antagonists ?

A
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19
Q

What are the second generation H1 receptor antagonists?

A
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20
Q

What are the actions of H1 receptor antagonists ?

A
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21
Q

How can H anatagonists be used for allergic conditions?

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22
Q

What are the uses of H antagonists for treating motion sickness & nausea?

A
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23
Q

What are somnifacients?

A
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24
Q

What are the adverse effects of H1 receptor antagonists?

25
Q

What are the H2 receptor antagonists?

26
Q

What are the uses of H2 receptor antagonists?

27
Q

What are the adverse effects of H2 receptor antagonists?

28
Q

What is the mechanism of action of serotonin?

29
Q

What are the serotonin agonists

30
Q

What are 5-HT1D/1B receptor agonists?

31
Q

What is metoclopramide?

32
Q

What is cisapride?

33
Q

What are serotonin antagonists?

34
Q

What is cyproheptadine?

35
Q

What is Ondansetron?

36
Q

What are ergot alkaloids?

37
Q

What is the mechanism of action of ergot alkaloids?

38
Q

How do we treat migraines?

39
Q

How do we treat hyperprolactinemia?

40
Q

How do we treat postpartum hemorrhage?

41
Q

How do we diagnose variant angina?

42
Q

What are the adverse effects of ergot alkaloids?

43
Q

What are the main subgroups of eicosanoids?

44
Q

What are the main source of eicosanoid?

45
Q

Where is arachidonic acid be found?

46
Q

Where are the 2 major pathways of eicosanoid synthesis?

47
Q

What is the COX pathway?

48
Q

What is Lipoxygenase pathway?

49
Q

What are the mechanisms of action of eicosanoids?

50
Q

What are the uses of eicosanoid- misoprostol?

51
Q

What is dinoprostone?

52
Q

What is Alprostadil?

53
Q

What is epoprostenol?

54
Q

What is latanoprostol?

55
Q

What are the types of eicosanoid antagonists?

56
Q

What are the leukotrienes pathway inhibitors?

57
Q

How do glucocorticoids of inhibiting leukotrienes synthesis ?

58
Q

How do NSAIDs inhibit leukotrienes pathway synthesis?