Adverse Effects Flashcards

1
Q

What are adverse effects?

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2
Q

How can adverse effects be used for positive effects?

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3
Q

What are the types of adverse reactions?

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4
Q

Describe type A adverse drug reactions

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5
Q

Describe Type B adverse drug reactions

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6
Q

What are type C adverse drug reactions?

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7
Q

What are type D drug reactions?

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8
Q

What are the main five mechanisms of drug toxicity?

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9
Q

What are On-target effects?

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10
Q

How can increase in biological response be caused by On-target drug interactions?

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11
Q

What is an off-target effect?

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12
Q

What are the different types of off-target drug effects?

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13
Q

How can a metabolite of a drug cause an adverse effect?

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14
Q

How can unconjugated NAPQI lead to cell death?

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15
Q

What are the two main harmful immune responses ?

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16
Q

Describe idiosyncratic toxicity

17
Q

What is an overdose?

18
Q

What are the mechanisms drug-drug interactions occur?

19
Q

What are the pharmacokinetics interactions?

20
Q

What is cytochrome P450?

21
Q

What are the cytochrome P456 inducer?

22
Q

What are the inhibitors of cytochrome P450?

23
Q

What are the pharmacodynamic reactions?

24
Q

What are the main examples of pharmacodynamics?

25
Q

What is the impact of Drug-herb interactions?

26
Q

Contrast acute and chronic toxicity

27
Q

What is apoptosis?

28
Q

What is fibrosis?

29
Q

What is carcinogenesis?

30
Q

What is teratogenesis ?

31
Q

How does the FDA categorize drugs?