Adverse Effects Flashcards

1
Q

What are adverse effects?

A
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2
Q

How can adverse effects be used for positive effects?

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3
Q

What are the types of adverse reactions?

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4
Q

Describe type A adverse drug reactions

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5
Q

Describe Type B adverse drug reactions

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6
Q

What are type C adverse drug reactions?

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7
Q

What are type D drug reactions?

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8
Q

What are the main five mechanisms of drug toxicity?

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9
Q

What are On-target effects?

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10
Q

How can increase in biological response be caused by On-target drug interactions?

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11
Q

What is an off-target effect?

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12
Q

What are the different types of off-target drug effects?

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13
Q

How can a metabolite of a drug cause an adverse effect?

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14
Q

How can unconjugated NAPQI lead to cell death?

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15
Q

What are the two main harmful immune responses ?

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16
Q

Describe idiosyncratic toxicity

A
17
Q

What is an overdose?

A
18
Q

What are the mechanisms drug-drug interactions occur?

A
19
Q

What are the pharmacokinetics interactions?

A
20
Q

What is cytochrome P450?

A
21
Q

What are the cytochrome P456 inducer?

A
22
Q

What are the inhibitors of cytochrome P450?

A
23
Q

What are the pharmacodynamic reactions?

A
24
Q

What are the main examples of pharmacodynamics?

A
25
Q

What is the impact of Drug-herb interactions?

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26
Q

Contrast acute and chronic toxicity

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27
Q

What is apoptosis?

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28
Q

What is fibrosis?

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29
Q

What is carcinogenesis?

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30
Q

What is teratogenesis ?

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31
Q

How does the FDA categorize drugs?

A