Cholinergic Agonists And Antagonists Flashcards

1
Q

What are the categorizes cholinergic drugs?

A
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2
Q

What are the types of cholinergic agonists ?

A
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3
Q

What are the Direct-Acting cholinergic agonists?

A
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4
Q

Where are the main cholinergic receptors in the body?

A
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5
Q

What are the direct effects of acetylcholine?

A
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6
Q

What are the cardiovascular effects of ACh?

A
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7
Q

What are the effects of ACh on vasculature (endothelial)?

A

Release of NO and vasodilation

Decrease in BP

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8
Q

What’s the effect of ACh on the eye iris?

A

Miosis

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9
Q

What’s the effect of ACh on ciliary muscle?

A

Accommodation of lens to near vision

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10
Q

What’s the effect of ACh of Bronchi?

A

Constriction; increased secretions

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11
Q

What is the effect of ACh on the heart?

A

Decreased heart rate,b decreased conduction velocity

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12
Q

What is the effect of ACh on the GI tract?

A

Increased tone, peristaltic activity & secretions; relaxation of sphincters

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13
Q

What is the effect of ACh on urinary bladder?

A

Contraction of detrusor muscle, relaxation of sphincter

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14
Q

What are the nicotinic receptors of ACh?

A
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15
Q

What are the main nicotinic receptors in the body?

A
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16
Q

What’s the impact of Dale’s experiment?

17
Q

What are the types of direct-acting cholinergic agonists?

18
Q

What are the choline esters?

19
Q

What are choline esters?

20
Q

What is acetylcholine and it’s uses?

21
Q

What is benthanechol? What are its uses?

22
Q

What is carbachol and it’s uses?

23
Q

What is methacholine and it’s uses?

24
Q

What are the natural alkaloids?

A

Pilocarpine & nicotine

25
Q

Describe pilocarpine

26
Q

What are the uses of pilocarpine?

27
Q

What are the adverse effects of muscuranic agonists?

28
Q

Describe nicotine

29
Q

What are the actions of nicotine in low doses?

30
Q

What are the actions of nicotine?

31
Q

Describe the acute poisoning of nicotine

32
Q

What are the clinical nicotine uses?

33
Q

What are the indirect-acting cholinergic agents (anticholinesterase)?

34
Q

What are the mechanism of action indirect-acting cholinergic agents(anticholinesterases)?

35
Q

What are the anticholinesterases?

36
Q

What are orangophosphates?