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Passmed Wrong Qs Notes > Oncology > Flashcards

Oncology Flashcards

1
Q

What chemo drug causes hypomagnesaemia?

A

Cisplatin

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2
Q

What is the side effect of bleomycin?

A

lung fibrosis

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3
Q

What is the side effect of doxorubicin?

A

Cardiotoxicity

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4
Q

What are the side effects of Cyclophosphamide and vincristine?

A

hyponatraemia

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5
Q

what are side effects of Cyclophosphamide?

A
  • hyponatraemia by causing SIADH, haemorrhagic cystitis and myelosuppression.
  • This treatment is also carcinogenic and may increase the risk of developing transitional cell carcinoma of the bladder.
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6
Q

What are the side effects of vincristine?

A

hyponatraemia, alopecia, peripheral neuropathy and constipation.

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7
Q

What does “focal sclerotic bony lesions” on a bone X-ray suggest?

A

metastasis

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8
Q

What increases the risk of cervical cancer?

A

HPV subtypes 16,18, 33

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9
Q

What HPV subtypes are the common cause of warts?

A

HPV subtypes 2,7,22

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10
Q

What HPV subtypes are associated with genital warts?

A

HPV subtypes 6 + 11 (not cancer)

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11
Q

What are the most common cancers that cause bone mets?

A

prostate
breast
lung (in order)

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12
Q

What is the most common side ( bone) of metastasis?

A

spine
pelvis
ribs
skull
long bones (in order)

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13
Q

What type of lung cancer secrets parathyroid hormone-related protein (PTHrP) causing hypercalcaemia?

A

Squamous cell cancer

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14
Q

What type of lung cancer causes cavitating lesions?

A

Squamous cell cancer

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15
Q

What are the tumour markers for Non-seminomatous testicular cancer?

A

Raised beta-human chorionic gonadotropin with a raised alpha-feto protein level

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16
Q

What are the tumour markers for seminomatous testicular cancer?

A

Raised beta-human chorionic gonadotropin only

17
Q

What type of anti-emetic is given after chemo?

A
  • dopamine receptor antagonist e.g. domperidone
  • 5HT3 antagonist e.g. ondansetron and granisetron
18
Q

What is given for pain in palliative patients with renal impairment?

A

Buprenorphine

Passmed Wrong Qs Notes (20 decks)

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