OB Flashcards
What hormones contribute to vascular engorgement and hyperemia during pregnancy?
Progesterone
Estrogen
Relaxin
The uterus receives __% of cardiac output
10
How much does CO increase through the stages of labor?
1st stage= ^ 20%
2nd stage= ^ 50%
3rd stage= ^ 80%
What causes decreased SVR/PVR in pregnancy?
Progesterone causes:
•increased nitric oxide -> vasodilation
• a decreased response to angiotensin & NE
Which stage of labor begins with the onset of perineal pain?
Second stage
Which local anesthetic reduces the efficacy of epidural morphine?
2-Chloroprocaine
(It antagonizes mu and kappa receptors in the spinal cord)
Why is lidocaine not used for continuous epidural infusion?
Tachyphylaxis and I crossed the placenta to a greater degree
What medications should be given for prophylaxis against aspiration?
Sodium citrate
H2 receptor antagonist (ranitidine)
Gastrokinetic agent (metoclopramide)
At what point are pregnant patients considered full stomachs?
18-20 weeks gestation
When is the highest risk for teratogenicity in the pregnant patient?
Organogenesis (day 13-60)
A healthy placenta produces thromboxane Nd prostacyclin in equal amounts; what is the ratio produced in a or with preeclampsia?
7 x more thromboxane than prostacyclin
The presence of _____ differentiates eclampsia from preeclampsia
Seizures
What is the antidote for mag toxicity?
10mL of 10% calcium gluconate IV
What type of placental disorder is a/w painless vaginal bleeding?
Placenta previa
6 risk factors for placental abruption
PIH
Preeclampsia
Chronic HTN
Cocaine abuse
Smoking
Excessive alcohol use
List 3 causes of DIC that occurs during labor and delivery
Amniotic fluid embolism
Placenta abruption
Intrauterine fetal demise