Coag Flashcards
1
Q
A
Factor deficiency or anticoagulation
2
Q
A
Impaired platelet number or function
3
Q
A
Primary fibrinolysis
4
Q
A
Hypercoagulation
5
Q
A
Stage 1 DIC: hypercoaguable state with secondary fibrinolysis
6
Q
A
DIC stage 2: hypocoaguable
7
Q
Platelet adhesion is a/w?
A
vWF
8
Q
Platelet activation and aggregation is a/w?
A
ADP & thromboxane A2
9
Q
Final common pathway
A
10, 5, 2, 1
(Think dollar denominations $10, $5, $2, $1)
10
Q
What is the mnemonic for the coagulation factors?
A
11
Q
A
12
Q
Which pathway is faster?
A
Extrinsic (15 sec) vs intrinsic (6 min)
13
Q
What 2 mechanisms turn off fibrinolysis?
A
- tPA inhibitor inhibits the conversion of plasminogen to plasmin
- Alpha-2 antiplasmin inhibits the action of plasmin on fibrin
