Nutrition for Cancer Flashcards

1
Q

1/3 of cancers in higher-income countries due to

A

poor nutrition
sedentary lifestyle
excess weight

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2
Q

what are the most common female cancers?

A

breast
lung
colorectal

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3
Q

what are the most common male cancers?

A

prostate
lung
colorectal

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4
Q

what diet increases the risk of cancer?

A
alcohol
processed meat
red meat
grilling meat
saturated fat
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5
Q

what diet decreases the risk of cancer?

A
plant-based diet
omega 3s
vitamin D
coffee 
tea
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6
Q

cancer protective phytochemicals

A
lycopene
anthrocyanins
alpha and beta carotene
beta cryptoxanthin
leutin, seaxanthin
sulforaphanes, indoles
allyl sulphides
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7
Q

lycopene

A

tomatoes
pink grapefruit
watermelon

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8
Q

antocyanins

A

berries
grapes
red wine
plums

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9
Q

alpha and beta carotene

A

carrots
mangos
pumpkin
sweet potato

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10
Q

beta cryptoxanthin

A
cantaloupe
peaches
oranges
papaya
nectarines
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11
Q

lutein, zeaxanthin

A

spinach
avocado
honeydew
turnip greens

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12
Q

sulforaphanes, indoles

A

cabbage
broccoli
brussel sprouts
cauliflower

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13
Q

allyl sulphides

A

onion
garlic
chives
leeks

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14
Q

underweight/malnourished people tend to present with what cancers?

A
head/neck
esophageal
gastric
pancreatic
lung
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15
Q

overweight/obesis people tend to present with what cancers?

A

breast
prostate
colon
all others

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16
Q

warburg effect

A

decrease in Kreb’s cycle and ETS (allows tumors to grwo in conditions irrespective of oxygen concentration
increase in glycolysis (lactate production produces the acidic environment favorin invasion

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17
Q

the warburg effect increases what?

A

glutamine usage

lipid synthesis

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18
Q

warburn effect is regulated by?

A

tumor suppressor genes and oncogenes

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19
Q

describe calorie restriction and cancer

A

decrease caloric intake by at least 30%
could be chronic or intermittent fasting
CR has been shown to decrease tumor initiation, promotion and progression

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20
Q

describ ketogenic diet and cancer

A

glucose deprivation increases oxidative stress in cancer cells
prevents pentose phosphate pathway from quenching ROS
less risks in adults following this diet

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21
Q

those on a ketogenic diet often have deficiencies in what?

A

selenium
copper
zinc

22
Q

cancer cachexia diagnosis?

A

weight loss >10%
caloric intake <1500 Cal/d
CRP >10 mg/L

23
Q

nutrition for cancer cachexia

A

high fat, high protein diet
nutritional support when warranted
early interventions using nutritional beverages
adequate phytochemicals

24
Q

for maintenance of body weight and lean tissue, how do you calculate protein and energy intake for those with cancer?

A

1-1.5 g/kg body weight

25-30 kcal/kg body weight daily

25
for weight regain and repletion of muscle tissue, how do you calculate protein and energy intake for cancer patients?
1.5-2.0g/kg body weight daily | 30-35kcal/kg body weight daily
26
general rule for fluid recommendations
20-40mL/kg or 1mL/kcal consumed 8oz=250mL
27
how should those with cancer get their vitamins and minerals
get from diet supplements considered only if deficiency is biochemically or clinically demonstrated only considered if intake is consistently <67% RDA check with oncologist first
28
how to manage anorexia/poor appetite
small, frequent nutrient dense meals and snacks add protein and calories to favorite foods keep nutrient dense foods nearby at all times eat most when feeling best eat in plesant atmosphere
29
how to manage nausea and vomiting
eat small, low fat meal in morning of first treatment clear liquid diet (room temp) for a few days after therapy begins avoid high fat, spicy or overly sweet food and foods with strong odors eat bland, soft, easy to digest foods
30
how to manage diarrhea
drink small amounts of electrolyte-containing fluid throughout the day avoid fruit juices avoid sugar alcohol containing foods decrease high fiber foods CRAM (cereal, rice, applesauce, milk) probiotic (lactobacilli, bifidobacterium) glutamine supplements
31
how to manage constipation
increase high fiber foods (nuts, legumes, fresh or cooked fruits and veggies, especially those with skins and seeds drink at least 64 oz fluid daily probiotics increase physical activity
32
how to manage sore throat, esophagitis
eat soft, moist foods with extra sauces avoid dry, coarse foods avoid alcohol, citrus, caffeine tomatoes, vinegar and hot peppers
33
mucositis
inflammation of epithelia cells lining the GI tract main cause of chemo-induced pain found in 40-70% of chemo patients
34
what are the mouth changes in most cancer patients?
change in tongue, lip or gum color, change in salivation, cracks, ulcers or lesions
35
how to manage mucositis
maintain good oral hygeine to prevent infection meet minimum protein requirements eat only soft, non-fibrous, non-acidic foods avoid alcohol, citrus, caffeine, tomatoes, vinegar, hot peppers eat room temp or chilled foods and fluid honey-swish and swallow DGL or glutamin supplements
36
how do manage fatigue
small, frequent meals and snacks easy to prepare or easy to eat foods keep nutrient dense foods nearby at all times eat most when feeling best
37
food safety in patients with neutropenia
avoid eating foods with unsafe levels of microorganisms (raw meat, unpasteurized foods, raw honey) wash hands before eating wash fruits and beggies focus on those that can be peeled keep foods at proper temperature during cooking and storage
38
what do you do with altered taste or smell
good oral hygeine try marinades or spices use plastic utensils eat cooler foods
39
what do you do with thicened saliva?
sip on liquids throughout the day try club soda, seltzer water or papaya nectar mucinex use a cool mist humidifier while sleeping
40
how to manage xerostomia
sip on liquids throughout the day (every 10 minutes) try tart foods to stimulate saliva, if sores not present eat soft, moist foods and use extra sauces avoid alcohol and alcohol containing antacid good oral hygeine artificial saliva or mouth moistureizers use a cool mist humidifier at night acupuncture
41
long term effects of surgical cancer treastment
``` lack of skin sensitivity body image issues sexual dysfunction numbness pain limited ROM weakness neuropathy ```
42
long term effcts of radiation to breast/chest region
``` fatigue skin sensitivity/pain sexual dysfunction pain asymmetrical breast volume lymphedema skin discoloration CVD lung fibrosis causing shortness of breath second primary cancer ```
43
long terms effects of chemotherapy
``` cogntive impairment fatigue infertility sexual dysfunction weight gain neuropathy oral health issues hair loss osteoporosis/osteopenia CVD leukemia ```
44
general psychosocial effects of cancer
``` depression distress worry/anxiety fear of recurrence fear of pain end of life concerns loss of sexual function and/or desire challenges with self image relationship and other social role difficulties return to work concerns or financial challenges ```
45
increases breast cancer
``` excess weight smoking age history of BC mutations of BRCA 1 and @ genes dense breast tissue years of estrogen exposure alcohol consumption ```
46
decreases breast cancer
``` first pregnancy before 35 breastfeeding mastectomy ovarian ablation exercise plant based diet with marine sources of omega 3s ```
47
increases prostate cancer
``` age genetics smoking excessive weight sedentary lifestyle adult height red meat high fat diet dairy ```
48
decrease prostate cancer?
plants (lycopene and sulforaphane)
49
increase colorectal cancer
``` age family history personal history of colorectal or ovarian cancer history of IBD alcohol smoking African American ecessive weight processed or red meats ```
50
decrease colorectal cancer
plants fish or omega 3s dairy vitamin D
51
increase lung cancer
smoking secondhand smoke radiation beta-carotene supplements in smokers
52
decrease lung cancer
plants | high intensity exercise