NSAIDS

Question 0

Lansoprazole

Answer 0

PPI- reduced ulcer relapse rates on patients on NSAIDs and ASA

Question 1

Aspirin overdose and treatment ?

Answer 1

salicylism - tinnitus and impaired hearing. Rapid breathing, respiratory alkalosis, lethargy, dehydration and hyperpyrexia. If severe coma, convulsions,metabolic and respiratory acidosis.

Treatment -sodium bicarbonatecharcoal

Gastric irritation, ulcer bleed

Question 2

Acetaminophen poisoning treatment ?

Answer 2

N-acetyl cysteine

-large doses of Tylenol reduced glutathione level

• exceeding 10-15 =liver failure
• exceeding 25g =fatal

Question 3

Ibuprofen dosage

Answer 3

Use at <1200mg/day

Question 4

Naproxen dosage ?

Answer 4

<1000mg/day

Question 5

Ketorolac

Answer 5

NSAID - Used post operatively
Given parentally

Poor anti -inflammatory , fever
Very good analgesic -pain

Question 6

Diclofenac

Answer 6

Most used but most A.E.^ CAD

Question 7

Indomethacin

Answer 7

NSAID used in acute gout ,RA, ankylosing spondylitis ,PDA (to close )

-do not use on patient on lithium (reduce urinary flw

Question 8

Osteoarthritis of hip and knee

Answer 8

Glucosamine and topical capsaicin

Question 9

Celecoxib

Answer 9

Only cox inhibitor still available .others increase cardiovascular events

Question 10

Acetaminophen

Answer 10

Reversible inhibits cox

4000mg/ day

Question 11

Acetaminophen increases effects of

Answer 11

Warfarin

Question 12

Cox 2 inhibitors

Answer 12

No stomach kidney involvement

Question 13

Polyethylene glycol

Answer 13

Osmotic ally draws water into GIT softness stool

Colonoscopy