16- Diabetes Flashcards
Sulfonylureas
Meglitinides
Stimulate pancreas the release insulin
Biguanides-metformin
Control hepatic glucose production
GLP-1 like agonist
Amylin analogs
Dipeptidyl peptidase 4- inhibitors
Drugs that mimic or prolong the action of inhibit hormones and inhibit glucagon secretion
Metformin
Biguanides- first drug of choice
Decreases hepatic glucose
Increases insulin glucose uptake
A.e. Diarrhea, abdominal discomfort
No weight gain
No hyperglycemia
If a patient develops lactic acidosis ?
Biguanides -metformin
Thiazolinediones
Pioglitazone
Rosiglitazone
Pioglitazone
Rosiglitazone
Thiazolidinediones
Reduce A1c
A.e Hypoglycemia
Weight gain
Contradicted in patients with CVD
Gliflozins
drugs that inhibit reabsorption of glucose
Alpha glycosidase inhibitors
Slow the absorption of starches
Ppar-y agonists GlitAzones
Slow the absorption of starches
Chlorpropramide
Tolbutamide
First generation solfonyureas
Glyburide
Glimepride
Gliprizide
Second generation sulfonyureas
Acarbose
Miglitol
Alpha glycosidase inhibitors