NS I - Nervous System Overview and Action Potentials Flashcards

1
Q

what are the overall functions of the nervous system

A

-muscle contraction
-integration of blood oxygen, carbon dioxide, and pH levels via respiratory activity
- regulation of volumes and pressures in the circulation via cardiovascular and urinary function
-digestive system motility and secretion

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2
Q

whats the difference between nervous system reflex and an endocrine system reflex

A

nervous system is quick fix and ES is slower long term maintenance

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3
Q

what is the functional unit of the NS

A

neurons

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4
Q

what are the two main divisions of the NS

A

afferent and efferent

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5
Q

what are the parts of the afferent NS

A

visceral and somatic

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6
Q

what are the parts of the efferent NS

A

somatic and autonomic

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7
Q

what are nissl bodies

A

clusters of ribosomes on neurons that make the cell body and tissue appear gray

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8
Q

what are internodes formed by

A

neuroglia cells such as oligodendrocytes (CNS) and Schwann cells (PNS)

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9
Q

what are internodes separated by

A

nodes of ranvier

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10
Q

what is the function of internodes

A

speed up the rate of nerve impulse conduction

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11
Q

which way does information flow in a neuron

A

from the cell body down the axon

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12
Q

what type of neurons are sensory neurons and where are they found

A

pseudounipolar and bipolar neurons found in afferent division of PNS

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13
Q

what do sensory neurons do

A

carry sensory information from reflex receptor to CNS

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14
Q

are sensory neurons myelinated

A

yes

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15
Q

what type of neurons are motor neurons and where are they found

A

multipolar neurons found in the efferent division of the PNS

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16
Q

where are cell bodies and dendrites of sensory neurons found

A

PNS with axons that extend into the CNS

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17
Q

what do motor neurons do

A

carry motor commands from CNS to effectors

18
Q

where are the cell bodies/dendrites of motor neurons found

A

in CNS axons extend into PNS

19
Q

what types of neurons are interneurons and where are they found

A

multipolar, anaxonic, found in the CNS only

20
Q

what do interneurons do

A

carry information from one neuron to another

21
Q

where are APs trigggered

A

at the axon hillock

22
Q

what are graded potentials

A

small changes in membrane potential of variable strength/amplitude

23
Q

whats the difference between graded potentials and APs

A

GPs last longer but only travel a short distance along membrane and lose strength as they travel

24
Q

what are examples of graded potentials

A

-synaptic potentials
-EPSPs
-IPSPs

25
are receptor potentials excitatory or inhibitory
excitatory
26
are end plate potentials excitatory or inhibitory
excitatory
27
whats happening in depolarization
Na+ moves into the cell through VG Na+ channels then VG Na+ channels close and slow VG K+ channels open
28
what happens during repolarization
K+ moves outside the cell through VG K+ channels
29
what happens during hyperpolarization
VG K+ channels still open then they close and return to resting membrane potential
30
what causes the absolute refractory period
the all or non activation and the voltage gated Na+ channels closed inactivation gates
31
what causes the relative refractory period
some sodium channels resetting to resting state after hyperpolarization
32
what would a potassium concentration between 3.5 mM and 6 mM do to a neuron
-increase membrane excitability -depolarizes membrane moving closer to threshold
33
what would a potassium concentration greater than 6 mM do to a neuron
-reduce membrane excitability -depolarizes membrane and cause inactivation of VG Na+ channels
34
what does hypokalemia do to to neuron excitability
reduces membrane excitability and hyperpolarizes membrane
35
what does hypercalcemia do to membranes
reduces membrane excitability
36
what does hypocalcemia do to membranes
increased membrane excitability
37
what is threshold potential
the Vm at which AP triggered which is usually around -50 mV
38
whats the difference between VG Na+ channels and VG K+ channels
sodium channels have an activation gate and an inactivation gate. potassium channels only have an inactivation gate
39
describe the process of generating an AP and local current flow
-a graded potential above threshold reaches the trigger zone - VG Na+ channels open and Na+ enters the axon - positive charge flows into adjacent sections of the axon by local current flow - local current flow from the active region causes new sections of the membrane to depolarize -the refractory period prevents backward conduction. loss of K+ from the cytoplasm repolarizes the membrane
40
what are the 2 ways to increase conduction velocity of AP
-if myelinated -increasing axonal diameter
41
what is saltatory conduction
AP jumps from node to node