NEW 3 Flashcards

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1
Q

Amino acid sequence of protein is written…

A

in DNA

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2
Q

RNA has a series of…

A

NONoverlapping three base “words” called codons

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3
Q

Transcription rewrites the DNA —> RNA, substituting..

A

U for T
Uracil for Thymine

A + U in RNA**

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4
Q

Each amino acid is…

A

specified by codon

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5
Q

__ codons are possible

A

64

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6
Q

Some amino acids have more than…

A

one possible codon

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7
Q

Genetic code decides how codons are…

A

translated into amino acids

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8
Q

Three nucleotides specify ONE…

A

amino acid in the genetic code

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9
Q

61 codons correspond…

A

to amino acids

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10
Q

AUG

A
  • START of TRANSLATION

- codes for methionine

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11
Q

3 “stop” codons signal…

A

end of translation

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12
Q

Genetic Code

A

is universal, shared by organisms from simple to complex

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13
Q

RNA molecule is _______ from gene

A

transcribed

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14
Q

RNA polymerase

A

RNA nucleotides linked by transcription enzyme

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15
Q

Promoter

A

nucleotide sequence signal = “start transcribing”

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15
Q

Cap and tail of extra nucleotides are added to ends of the mRNA to…

A
  • help RNA leave nucleus
  • protect RNA from damaging enzymes
  • help RIBOSOMES bind to mRNA
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16
Q

INITIATION

A

RNA polymerase CONNECTS to promoter

17
Q

ELONGATION

A
  • amino acids added ONE by ONE

- RNA grows longer

18
Q

Removes introns and joins exons producing continuos coding sequence

A

RNA splicing

19
Q

TERMINATION

A
  • RNA polymerase reaches base in DNA template called TERMINATOR, signals the END of gene
  • polymerase detaches from RNA molecule and gene
20
Q

tRNA molecules

picks up _____ _____ and brings them to _______

A

amino acids

cytoplasm

21
Q

Translation - can be divided into same…

A

three phases as transcription:

1 ) initiation

2) elongation
3) termination

22
Q

Ribosomes are composed of…

A

ribosomal rRNAs and protein

23
Q

Ribosomes have binding sites for…

A

mRNA and tRNAs

24
Q

Messenger RNA (mRNA)*

A

-encodes amino acid sequence

25
Q

tRNA molecules use special…

A

TRIPLET of bases called anticodon

26
Q

P site

A

first tRNA occupies the p site, which holds growing polypeptide chain

28
Q

A site

A

available for next tRNA (transfer RNA)

28
Q

Translation termination

A
  • ribosome reaches STOP codon
  • completed polypeptide is released from the last tRNA
  • ribosome goes back into separate subunits
29
Q

3 types of Mutations

A

1) base substitution
2) insertions
3) deletions

30
Q

anticodon

A
  • triplet bases

- complements codons in mRNA

31
Q

Any change in nucleotide sequence of DNA

A

mutation

32
Q

Base substitution

A

1) have NO effect, silent mutation
2) leads to IMPROVED protein that helps enhance survival
3) nonsense mutation

33
Q

Mutations can involve large chromosomal regions or…

A

just single nucleotide pair

34
Q

Mutations caused by…

A

random errors during DNA replication

35
Q

Mutagens: cause _______

A

mutations

ex. high energy radiation, chemicals

37
Q

Nonsense mutation

A

CHANGES amino acid into stop codon

38
Q

Insertions & Deletion mutations

A
  • alter reading frame
  • produce NONFUNCTIONAL polypeptide
  • change in amino acid sequence downstream of mutation
38
Q

Codons are ____ to each other, NO gaps in between

A

next

39
Q

mRNA contains INtrons…

A

interrupts sequences that separates exons