NEW 2 Flashcards
DNA ligase
JOINS small fragments into continuous chain
Transcription is
DNA –> RNA in nucleus
Non-disjunction
change in chromosome # during MEIOSIS
DNA Polymerase
Unattached nucleotides polymerized into new strand
Translocation
- changes chromosome structure
- two NON-homologs exchange parts
X Chromosome Inactivation
-happens during embryo
development in FEMALE mammals
-male/female have one “ACTIVE X” in cells
Complementary Base Pairing Rules***
- A with T
- G with C
DNA replication occurs in 5 to…
3 directions (new strand)
DNA polymerases and DNA ligase also repair DNA…
damaged by radiation / toxic chemicals
Either mother’s or father’s X may…
become inactive
DNA replication proceeds in two directions at
many origins of replication at once
Protein Therapy
gives patients protein they lack
ex. clotting factor for hemophiliacs
Once X becomes inactivated in cell, ALL parts of cell
have SAME inactive X
Early identification of genetic disorders are important for…
prevention & treatment
Physiological Therapy
baby w/ PKU removes phenylalanine from diet