Neurotoxins Flashcards
0
Q
Batrachotoxin, aconitine, veratridine, and scorpion venom
A
Block Na channels by binding to their receptors OR by holding the voltage sensor (S4 segment of alpha1 subunit) at extracellular position
*Some neurotoxins also block Ca or K channels (w-conotoxins from snail and charybdotoxin from scorpions)
1
Q
Tetrodoxin (TTX) / saxitoxin
A
From pufferfishes and algae,
*Bind to and block sites near the surface of Na channels
2
Q
Neurotoxin effects
A
rapid paralysis, seizure, and death
