neurology of systemic dz

Question 1

most common neurologic complication in children with Hb SS dz.

Answer 1

Ischemic stroke (more common than hemorrhagic stroke in kids).

Question 2

Antibody found in cases of demyelinating polyneuropathy with IgM MGUS

Answer 2

anti myelin associated glycoprotein (MAG)

Question 3

hemolytic anemia
thrombocytopenia
renal dysfunction
neurologic signs
fever

Answer 3

TTP

Question 4

hemolytic anemia renal failure and thrombocytopenia preceded by abdominal pain and diarrhea.

Answer 4

HUS

Question 5

TIPS procedure in portal hypertension due to liver cirrhosis.

Answer 5

increases risk of hepatic encephalopathy

Question 6

pathologic hallmark of hepatic encephalopathy

Answer 6

Alzheimer type II astrocyte.

Question 7

atrophy of intestinal villi, loss of purkinje cells in cerebellum

Answer 7

celiac’s disease

Question 8

cranial nerve VII palsy, tongue fissuring, angioedema

Answer 8

Melkersson Rosenthal syndrome, IBD

Question 9

vascular complications in patients with IBD

Answer 9

venous and arterial thrombosis, increased risk during disease flares.

Question 10

pseudomyotonia

Answer 10

hypothyroid

Question 11

most common treatable cause of mental retardation

Answer 11

congenital hypthyroid

Question 12

most common eye movement abnormality in thyroid eye disease

Answer 12

restricted upward gaze

Question 13

multiple cranial neuropathies including sensorineural hearing loss, thick skull, increased alk phos

Answer 13

osteopetrosis

Question 14

diagnostic tests in Sjorgen’s syndrome

Answer 14

anti-Ro, anti-La, Schirmer test, minor salivary gland biopsy

Question 15

necrotising vasculitis with asthma, eosinophilia and sinus/pulm dz.

Answer 15

Churg-Strauss Syndrome

Question 16

necrotising vasculitis with glomerulonephritis, paranasal sinusitis and pulm dz, C-ANCA +

Answer 16

Wegner granulomatosis

Question 17

vasculitis associated with chronic hep B, livedo reticularis, subcutaneous nodules, multi-organ involvement.

Answer 17

PAN

Question 18

recurrent orogenital lesions and positive pathergy skin test, brainstem inflammation

Answer 18

Bechets disease

Question 19

most common presentation of neurosarcoidosis

Answer 19

Cranial neuropathy- usually CN VII.

Question 20

blood supply of pituitary

Answer 20

branches of ICA

Question 21

cells that synthesize ADH and oxytocin

Answer 21

magnocellular neurons in supraoptic and paraventricular hypthalamic nuclei.

Question 22

hypernatremia with polydipsia and polyuria

Answer 22

DI

Question 23

hypernatremia with clinical signs of hypovolemia

Answer 23

cerebral salt wasting

Question 24

hyponatremia after brain injury

Answer 24

SIADH