Neuroleptika Flashcards

1
Q

Clozapin (SUB, W, K, UAW)

A

SUB: atypisches Neuroleptikum
W: Initial dämpfend, stark antipsychotisch
K: CYP1A2
UAW: Agranulozytose, Gewichtszunahme, Hypersalivation!, stark anticholinerg

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2
Q

Olanzapin (SUB, K, UAW)

A

SUB: atypisches Neuroleptikum
K: CYP1A2
UAW: EPS, Spät-Dyskinesien, Gewichtszunahme, Schläfrigkeit

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3
Q

Aripripazol

A

partieller Agonist an D2-Rezeptoren –> Linderung Parkinson, aber mehr Erregung

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4
Q

Typische Neuroleptika

A

Chlorproamzin, Perazin, Fluphenazin, Flupentixol, Haloperidol

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5
Q

Atypische Neuroleptika

A

Clozapin, Olanzapin, Rsiperidon, Sulpirid, Quetiapin, Zibrasidon, Aripiprazol

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6
Q

Sulpirid, Amisulprid (K)

A

bindet an D2-Rezeptoren, hochselektiv; nicht H1, M, Zero

Verwandtschaft mit Metoclopramid: D2-Antagonist, 5HT3-Antagonist, 5HT4 Agonist

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7
Q

Risperidon

A

keine M-Rezeptoren Aktivität

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