Neurodevelopment

Question 1

6 Stages of Neurodevelopment

Answer 1

1) Neurogenesis
2) Cell Migration
3) Cell Differentiation
4) Synaptogenesis
5) Neuronal Cell Death
6) Synapse rearrangment

Question 2

Neurogenesis

Answer 2

Production of neurons in ventricular zone inside neural tube

Question 3

Cell Migration

Answer 3

Cells move away from ventricular layer, once they reach target destination they begin to express particular genes to make proteins they need

Question 4

Cell Differentiation

Answer 4

Allows cell to acquire its specific appearance and fuction

Question 5

Synaptogenesis

Answer 5

Cells in developing brain form synapses with each other

Question 6

Cell-Cell Interactions

Answer 6

developmental process by which one cell affects the differentiation of another

Question 7

Cell Death

Answer 7

Apoptosis

Neurons compete for synaptic connections and neurotrophic factors

Question 8

Synapse Rearrangment

Answer 8

After period of cell death, neurons grow longer and more elaborate dendrites with many new synapses

Question 9

Postnatal development of Cortex

Answer 9

Net loss of synapses from childhood to adolescence

Question 10

Brain Changes as we Age

Answer 10

Memory impairment correlates with shrinkage of hippocampus

Hippocampal volume correlates with delayed recap store

Question 11

Dementia

Answer 11

drastic failure in cognitive ability including memory failure and disorientation

Question 12

Alzheimers

Answer 12

form of dementia that appears before age 65 where brain exhibits cortical atrophy and reduced metabolism

Question 13

Cellular Changes of Alzheimers

Answer 13

1) Patches of amyloid plaques formed by beta-amyloid buildup
2) Neurofibrillary Tangles: abnormal wholes of filaments
3) Loss of neurons that produce acetylcholine in basal forebrain