Homeostasis Flashcards
Homeostasis
Maintenance of stable, balanced, internal environment controlled mainly by negative feedback
Redundancy
Physiological systems can be monitored by more than one mechanism
Allostasis
Process of achieving homeostasis
Allostatic Load
Associated cost of home so static responses
Sympathetic Stress Response
Short term, fast acting stress response
Danger signal- sensory cortex- Locus ceruleus- adrenal medulla- fight flight response
Hypothalamic Pituitary Adrenal axis
Long term
Activation- hypothalamus- anterior pituitary- adrenal cortex- relaxes cortisol
Hypovolemic Thirst
Low extra cellular water volume from loss of body fluids
Detected by Baroreceptors located in blood vessels and heart
Osmotic thirst
High extra cellular solute concentration (salty fluids)
Osmosensory neurons in hypothalamus monitor changes in concentration of extra cellular fluids
Angiotensin II
Hormone that increases blood pressure by constricting blood vessels
Glucose
Principle sugar used for energy
Glycogen
Glucose stored in liver and muscles for short term regulated by insulin
Insulin
Helps glucose transporters import glucose from blood into cells
Diabetes mellitus
Failure of insulin to induce glucose absorption
Type 1: juvenile onset, pancreas stops producing insulin
Type 2: adult onset reduced tissue sensitivity to insulin
Basal Metabolism
Energy used for heat production, maintenance of membrane potentials and life sustaining processes
Ventromedial hypothalamus
Satiety center of brain
Lateral Hypothalamus
Hunger center
Hypothalamic appetite control
Hormones from body drive hypothalamic appetite control via circuit within actuate nucleus
Leptin
Fat cells release leptin into blood stream to provide info to brain about long term energy stores
Short term energy hormones
Ghrelin: appetite stimulant
PYY-3-36: appetite suppressant
Appetite control neurons
POMC: satiety neuron inhibits appetite and increases metabolism
NPY: hunger neuron stimulates appetite and reduced metabolism
Nucleus of Solitary tract (NST)
Appetite signals converge on NST in brain stem