neuro part 2 (3) Flashcards
what is inflammation of the meninges
meningitis
what 2 things cause meningitis?
bacteria or virus
why has incidence of meningitis decreased?
increased protection from several vaccines
patho of meningitis
bacteria in blood spreads to CNS, enters subarachnoid space → inflammatroy response occurs → bacterial endotoxins cause inflammation/edema in brain → cerebral edema / inc. ICP occur as a result of the presence of the endotoxins
which of the following are manifestations of an INFANT with meningitis
1. fever
2. poor feeding
3. anterior fonanel bulging
4. calms with rocking/cuddling
5. vomit/diarrhea
6. irritable/fussy
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which of the following are clinical manifestations of a CHILD with meningitis
1. irritable
2. lethargy
3. inc. appetite
4. frontal headache
5. photophobia
6. nuchal rigidity
7. fever
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describe nuchal rigidity
hallmark sign of meningitis, chin to shest, pain in back of neck
what is resistance to neck flexion?
nuchal rigidity
describe fevers in bacterial vs. viral meningitis
high fever = bacterial, low grade fever = viral
diagnostic tests of meningitis
CBC, elec, BUN/cr., LUMBAR PUNCTURE, positive brudzinski/kernig sign
which sign is characterized by:
-when you flex the neck, the hips and knees will flex
Brudzinski sign (indiciative of meningitis)
which sign is characterized by:
-when you flex the leg at the hip and knee, and then extend the knee, it will cause pain and increased resistance
kernig sign (indicative of meningitis)
how long are antibiotics used for meningitis
7-21 days at the highest dose
what med is used for meningitis if the infant is older than 6 weeks
dexamthasone (decreases neuro damage)
what is always done prior to administering the first dose of antibiotics for meningitis
lumbar puncture
describe urinary output in peds
<=12 = 1ml/kg/he
>12 = 0.5ml/kg/hr
what is acute encephalopathy / cerebral dysfunction caused by toxic, inflammatory, or anoxic insult or injury that may result in permanent tissue damage
reye syndrome
what is associated with causing reye syndrome?
use of aspirin in influenza and varicella
what percentile head size classifies microcephaly
less than 3rd %ile
what is common with microcephaly
intellectual disability
causes of microcephaly
- genetics
- destructive insult during fetal life due to infection, metabolic disorder, hypoxia-ischemia
- maternal infection
what is an imbalance between the producation and absorption of CSF, there is inc. CSF and enlargement of ventricles
hydrocephalus
which kind of fluid imbalance is common with myelomeningocele
hydrocephalus
what can hydrocephalus be a complication of?
illness (meningitis/brain tumor)
injury
what is CSF produced by
choroid plexus within ventricles
where does CSF flow?
ventricles, brainstem, spinal cord, and surface of brain
is communicating hydrocephalus acquired or born with?
acquired
what is impaired in communicating hydrocephalus
asborption of CSF in sub-arachnoid spaceand arachnoid villi
what is caused by a blockage in the ventricular system that prevents CSF from entering the subarachnoid space resulting in enlargement of one or more ventricles
non-communicating hydrocephalus
what are causes of non-communicating hydrocephalus
infection, hemorrhage, tumor, surgery or structural deformity
T/F?
in infants the predominant manifestation in hydrocephalus is rapidly increasing head circumference
true
what are some early clinical clinical manifestations of ↑ ICP
- Rapidly increasing head circumference if under 18 months
- Tense, full, or bulging anterior fontanel
- Split sutures in an infant
- Frontal bossing which is protrusion of the frontal area of the head
- Difficulty holding head up
- Macewen sign with percussion (cracked pot sound)
- Prominent distended scalp veins
- Increase tone or hyperreflexia, Babinski sign
- Irritability or lethargy
- Poor feeding, nausea and vomiting
- Decline in level of consciousness
late clinical manifestations of increaced ICP
- Cushings triad: Increased systolic BP with wide pulse pressure, bradycardia, irregular respirations
- Shrill high pitched cry
- Difficulty feeding, vomiting
- Regression in milestones
- Significant change in Level of consciousness
- Fixed and dilated pupils
- Seizures
what are some signs of acquired hydrocephalus after closure of infant scalp sutures?
- Signs of increased intracranial pressure
- Headache upon wakening with nausea and vomiting
- Irritability or lethargy
- Altered level of consciousness
- Personality changes
- Poor judgement, poor school performance, memory loss
- Visual problems
how is hydrocephalus diagnosed?
- head circumference
- clinical manifestations of ↑ ICP
- CT/MRI
- can be prenatal w/ US
treatment of hydrocephalus
- surgery to remove obstruction
- ventriculo-peritoneal shunt
what 4 things does a ventriculo-peritoneal shunt consist of?
- ventricular catheter
- pumping chamber
- one way pressure valve
- distal catheter
what are less serious complications of ventriculo-peritoneal shunt
- blockage
- kinking of tubing
- valve breakdown
what is the most serious complication of ventriculo-peritoneal shunt
infection (often within 3 months)
what happens if a VP shunt malfunctions?
revisions
post-op care after VP shunt for hydrocephalus
- assess/vs
- HOB flat initially (prevents rapid CSF drainage), then elevated over next 1-2 days to promote drainage
- surgical site assessment
- I&O
- pain management
- education of infection risk, sx of ↑ ICP from shunt failure
describe HOB elevation after VS shunt surgery for hydrocephalus
HOB flat initially to prevent rapid CSF drainage, then elevated over 1-2 days to promote drainage