neuro diseases Flashcards
normal eyes but the cow is blind
lead or PEM/polio
look for nutritional cause or lead source
lead has GI signs
you have a neuro case you have localized to the brain. what do you want to treat it with
10mg/kg thiamine. antiinflammatories
what is our drug that we know penetrates the BBB
florphenicol
blindness, hyperesthesia,
lead, pem/polio, water deprivation
what does PEM cause
lack of thiamine, needed for brain energy metabolism. cerebrocorticonecrosis from brain swelling
what causes PEM
primary lack of thiamine or sulfur induced. both have the same treatment but for sulfur induced you treat longer.
what is the treatment for lead toxicosis
calcium edta and thiamine. ethical delimma about treatment because sketchy slaughter WD
pump rumen
cow is dull but not systemically ill. seems off neurologically. had respiratory disease a week ago
TEME from h. somni
what is the signalment of TEME
feedlot cattle sleeping sickness
what is the treatment and prognosis of TEME (h. somni)
PREVENTION with CTC
florphenicol (for resp dz-BBB) antiinflamatory
poor prognosis- infection in the brain
circling, facial nerve deficits, head tilt
listeria. think about abortions in gravid cows
how does listeria cause neurologic disease
climbs up the cranial nerves from the oral mucosa
what do we need to remember about water deprivation
slow introduction of water. 1-3 gallons e 6 hours until they arent begging
what is the treatment for water deprivation
slow water introduction
steroids
1ml/lb hypertonic saline
dropped elbow, inability to extend the arm
radial nerve paralysis
stiff gait, third eyelid protrusion, reactive to noise
tetanus. vaccinate if nervous
bilaterally symmetric neuro signs and blindness in a sheep. ddx
PEM, lead, sulfur, salt tox,
unilateral CN defecits sheep
listeria monocytogenes- microabscessations
paralysis, ataxia, toe dragging, dog sitting in sru
likely meningeal worm
treatment for meningeal worm
5x dose for 5 days
50 mg/kg fenben for 5 days
+- injectable ivermectin
antiinflammatories
CFS with glucose lower than serum
likely bacterial meningitis and the bacti are using up the glucose
tx for bacti meningitis SRU
ceftiofur sodium
what can cause listeria
feeding silage at >5.5 pH
basophilic stippling in blood smear
lead tox. supportive care
intense pruritis, wasting, bunny hopping
scrapie
what is scrapie
prion disease. like CWD. prpsc
how to diagnose scrapit
histo- noninflam vacuolar degeneration of grey matter
PrPsc in lymphoid tissue THIRD EYELID
what genes do we look at in breeding resistant scrapie flocks
codon 171.
RR sheep or R_ sheep
what genetic combos for scrapie are a no breed/terminal lines only breeding
QQ sheep
unsure if the CNS signs are bacterial, parasitic or PEM. what do you do
can CFS tap, look for low glucose, eos.
tx with thiamine +_-abx if unsure
where do we csf tap sru
LS site
