neuro diseases

Question 1

normal eyes but the cow is blind

Answer 1

lead or PEM/polio

look for nutritional cause or lead source

lead has GI signs

Question 2

you have a neuro case you have localized to the brain. what do you want to treat it with

Answer 2

10mg/kg thiamine. antiinflammatories

Question 3

what is our drug that we know penetrates the BBB

Answer 3

florphenicol

Question 4

blindness, hyperesthesia,

Answer 4

lead, pem/polio, water deprivation

Question 5

what does PEM cause

Answer 5

lack of thiamine, needed for brain energy metabolism. cerebrocorticonecrosis from brain swelling

Question 6

what causes PEM

Answer 6

primary lack of thiamine or sulfur induced. both have the same treatment but for sulfur induced you treat longer.

Question 7

what is the treatment for lead toxicosis

Answer 7

calcium edta and thiamine. ethical delimma about treatment because sketchy slaughter WD
pump rumen

Question 8

cow is dull but not systemically ill. seems off neurologically. had respiratory disease a week ago

Answer 8

TEME from h. somni

Question 9

what is the signalment of TEME

Answer 9

feedlot cattle sleeping sickness

Question 10

what is the treatment and prognosis of TEME (h. somni)

Answer 10

PREVENTION with CTC
florphenicol (for resp dz-BBB) antiinflamatory

poor prognosis- infection in the brain

Question 11

circling, facial nerve deficits, head tilt

Answer 11

listeria. think about abortions in gravid cows

Question 12

how does listeria cause neurologic disease

Answer 12

climbs up the cranial nerves from the oral mucosa

Question 13

what do we need to remember about water deprivation

Answer 13

slow introduction of water. 1-3 gallons e 6 hours until they arent begging

Question 14

what is the treatment for water deprivation

Answer 14

slow water introduction
steroids
1ml/lb hypertonic saline

Question 15

dropped elbow, inability to extend the arm

Answer 15

radial nerve paralysis

Question 16

stiff gait, third eyelid protrusion, reactive to noise

Answer 16

tetanus. vaccinate if nervous

Question 17

bilaterally symmetric neuro signs and blindness in a sheep. ddx

Answer 17

PEM, lead, sulfur, salt tox,

Question 18

unilateral CN defecits sheep

Answer 18

listeria monocytogenes- microabscessations

Question 19

paralysis, ataxia, toe dragging, dog sitting in sru

Answer 19

likely meningeal worm

Question 20

treatment for meningeal worm

Answer 20

5x dose for 5 days
50 mg/kg fenben for 5 days
+- injectable ivermectin

antiinflammatories

Question 21

CFS with glucose lower than serum

Answer 21

likely bacterial meningitis and the bacti are using up the glucose

Question 22

tx for bacti meningitis SRU

Answer 22

ceftiofur sodium

Question 23

what can cause listeria

Answer 23

feeding silage at >5.5 pH

Question 24

basophilic stippling in blood smear

Answer 24

lead tox. supportive care

Question 25

intense pruritis, wasting, bunny hopping

Answer 25

scrapie

Question 26

what is scrapie

Answer 26

prion disease. like CWD. prpsc

Question 27

how to diagnose scrapit

Answer 27

histo- noninflam vacuolar degeneration of grey matter PrPsc in lymphoid tissue THIRD EYELID

Question 28

what genes do we look at in breeding resistant scrapie flocks

Answer 28

codon 171. RR sheep or R_ sheep

Question 29

what genetic combos for scrapie are a no breed/terminal lines only breeding

Answer 29

QQ sheep

Question 30

unsure if the CNS signs are bacterial, parasitic or PEM. what do you do

Answer 30

can CFS tap, look for low glucose, eos. tx with thiamine +_-abx if unsure

Question 31

where do we csf tap sru

Answer 31

LS site