Neuro Disease of Pigs

Question 1

Occurs in newborn piglets when the BG is <50

Answer 1

Hypoglycemia

Question 2

What are clinical signs of hypoglycemia?

Answer 2

Convulsions, shivering, hypothermia, gait abnormalities

Question 3

How do you dx pig hypoglycemia?

Answer 3

BG, empty stomach of dead pig

Question 4

How do you treat hypoglycemia in a pig?

Answer 4

20mL/kg 5% glucose, warm them up

Question 5

How do you control hypoglycemia in pigs?

Answer 5

Make sure sow is milking enough for litter

Question 6

What age of pigs is affected by Streptococcal meningitis?

Answer 6

3-12wk

Question 7

What is the causative agent of Streptococcal meningitis in pigs?

Answer 7

Strep suis

Question 8

What are neuro clinical signs of Strep suis?

Answer 8

Tremors, blindness, ataxia, convulsions

Question 9

What are non-neuro clinical signs of Strep suis?

Answer 9

Fever, anorexia, depression

Question 10

How do you dx Streptococcal meningitis in pigs?

Answer 10

Culture CSF/meningeal swab

Question 11

What will you see on necropsy of a pig with Streptococcal meningitis?

Answer 11

Suppurative meningitis

Question 12

How do you treat Streptococcal meningitis?

Answer 12

Penicillin, enrofloxacin, ceftiofur (must be quick)

Question 13

Water deprivation causes what?

Answer 13

Salt poisoning

Question 14

What does water deprivation/too much salt cause in the brain?

Answer 14

Hyperosmolarity = swelling and edema of brain

Question 15

What are clinical signs of salt poisoning>

Answer 15

Thirst, constipation, blindness, convulsions

Question 16

How do you dx salt poisoning?

Answer 16

History and clinical signs

Question 17

What will you see on histopath of a salt poisoning case?

Answer 17

Eosinophilic meningitis

Question 18

What part of the brain must you submit to get a diagnosis for neuro conditions in a pig?

Answer 18

The entire brain

Question 19

What causes edema disease in pigs?

Answer 19

E. coli

Question 20

What toxins does E. coli assoc. w/edema disease have?

Answer 20

Shiga like toxin, F18 pili

Question 21

How does the shiga like toxin of E. coli cause edema?

Answer 21

Vascular injury

Question 22

What pigs are most commonly affected by E. coli edema disease?

Answer 22

1-3wk post-weaning

Question 23

What are clinical signs of edema disease?

Answer 23

Sudden death, palpebral edema, ataxia, convulsion, scours

Question 24

How do you diagnose edema disease?

Answer 24

Pure culture from SI or colon, detection of toxin

Question 25

How do you prevent edema disease?

Answer 25

Vaccine pre-weaning (oral MLV)