Neuro Flashcards
describe the who classification for neuro tumours
1 - pilocytic
2 - low grade astrocytoma
3 - anaplastic astrocytoma
4 - GBM
bipolar cells with long hair like projections
pilocytic
who gets pilocytic tumours
children and young adults - good prognosis
where are low grade astrocytomas usually?
frontal and temporal lobes
who gets gbm
older people
butterfly appearance
gbm
where are gbms usually ?
frontal temporal parietal
what does gbm usually respond to?
temozolamide
which tumour has the best prognosis
oligodendorglioma
toothpaste appearance
oligodendorglioma
who gets oligodendrogliomas and where are they usually
25-45yo
frontal lobe
who is at risk of meningioma
nf2
describe the pathology of meningioma
extraaxial and usually do not infiltrate the brain
arachinoid cap
extraaxial and usually do not infiltrate the brain
arachinoid cap
meningioma
what is a haemangioblastoma
benign cystic highly vascular lesion
who is at risk of a haemangioblastoma
VHL syndrome
where are haemangiomas usually foudn
posterior fossa - cerebellar dysfucntion
What are the main secondary brain tumours
Lung breast GI but any mainly
What are the 5 main benign brain tumours
Pituitary adenomas Craniopharyngioma Meaningioma Acoustic neuroma Dermoid tumour
Describe a primary cerebral lymphoma and how you treat it
HIV related Steroids chemo (methotrexate based) +\- XRT
Treat GBM
Temozolamide
NF1 causes what type of brain tumour
Acoustic neuroma
Tuberous sclerosis causes what type of brain tumour
Astrocytoma
Men type 1 causes what type of brain tumour
Pituitary macroadenoma
