Colorectal Flashcards
1
Q
When does a person get screened for bowel cancer via foecal occult
A
50-74yos every 2 years
2
Q
What are the main types of mutations seen in colorectal cancer
A
APC mutation
KRAS mutation
P53 mutation
3
Q
What’s the main risk factor for colorectal cancer
A
Red meat
4
Q
What is the malignant evolution of a polyp
A
Adenocarcinoma
5
Q
Describe HNPCC
A
DNA mismatch repair mutation (<100 polyps)
Late onset
Aut Dom
Right sided
6
Q
Describe FAP
A
APC gene mutation >100 polyps Early onset Aut Dom Adenocarcinoma
