Chemotherapy Flashcards
What does adjuvant treatment mean
To reduce cancer recurrence
What does neoadjuvant treatment mean
To down stage tumour prior to surgery or radical treatment
What does radical chemo mean
With curative intent
How can chemo be given?
Oral IV local intraarterial subcut IM
What is prophase
Sister chromatids condense
Mitotic spindle assembles
Nuclear envelope breaks down
What is metaphase
Centromeres half way between spindle poles
Microtubules align chromosomes
What is anaphase
Separation of sister chromatids at centromere moving towards poles
Cell division starts
What is telophase
Nuclear membrane reforms
Chromosomes become extended
Cell division completes
What are the 5 types of chemo drug agents
Antitunour antibiotics Antimicrotubuke agents Alkalatibg agents Hormones or cytokines Monoclonal antibodies
What are the 4 main complications of chemo?
Bone marrow cupressuon Neutropenia Anaemia Thrombocytopenia Organ toxicity
What are the 4 main side effects of chemo
Marrow
Alopecia
Fatigue
Vomiting
What is extravasation
Chemo drug leaks outside the vein causing damage to the surrounding tissue
