Nervous System/Pain Meds

Question 0

Anti-parkinson, for tx of Parkinson’s EPS, including drug induced EPS. SE: anticholinergic S/S as dry mouth, blurred vision, urinary retention, constipation, confusion.

Answer 0

G: benztropine

B: Cogentin

Question 1

Anti-parkinson agent. Acts to replace dopamine levels in CNS. SE: N&V, orthostatic HP, dark urine, phych S/S(Hallucinations, paranoid ideation) disrhythmias

Answer 1

G: levodopa/carbidopa

B: Sinemet

Question 2

Anti-Alzheimer’s agent, cholinesterase inhibitor so increase Ach. SE: cholinergic S/S as N&V, diarrhea, dyspepsia, bronchoconstriction (caution w/ asthma and COPD pt.

Answer 2

G: donepezil

B: Aricept

Question 3

Barbiturate anti-convulsant, sedative/hypnotic. Sched IV, tx of partial & generalized T-C seizures. ck bld levels: 15-40 mcg/mL, more often used with kids than adults SE: lethargy.

Answer 3

PHENobarbital

Question 4

Anticonvulsant, esp for tonic-colonic & partial seizures. Also a cardiac antidysrhythmic. ck blood levels: 10-20 mcg/mL, do not abruptly DC. SE: pink urine, gingival hyperplasia, ataxia, nystagmus, Diplopia, agranulocytosis.

Answer 4

G: phenytoin

B: Dilantin

Question 5

Benzodiazepine anticonvulsant, also muscle relaxer, sedative, anti anxiety. Sched IV, esp for tx of status epilepticus. SE: sedation,dizziness,nausea,dry mouth,urinary retention,constipation,rash. Do not abruptly DC.

Answer 5

G: diazepam

B: Valium

Question 6

Skeletal muscle relaxant, antispasmodic agent. SE: drowsiness,urinary retention,constipation,lowers BP,rash, don’t abruptly DC

Answer 6

G: baclofen

B: Lioresal

Question 7

Anti-inflammatory, immunosuppressant in large doses. SE: increase risk of infections, osteoporosis, skin thinning, hyperglycemia, GI ulcer, adrenal gland suppression. Slow wound healing.

Answer 7

G: predniSONE

B: Deltasone

Question 8

NSAID, Cox1&Cox2 enzyme inhibitor, platelet aggregate inhibitor. SE: N&V, GI upset and bleed, tinnitus(toxicity sign) not for kids, risk for Reyes.

Answer 8

ASA, aspirin

Question 9

NSAID, Cox1&Cox2 enzyme inhibitor. Causes less bleeding than ASA, but less aggregation inhibition so no MI protection.

Answer 9

G: Ibuprofen

B: Motrin, Advil

Question 10

2nd generation NSAID, Cox2 inhibitor. SE: GI upset but less risk of GI bleed than Cox 1 inhibitors, rash, poss increase risk if MI, CVA

Answer 10

G: celecoxib

B: CeleBREX

Question 11

NSAID, Cox1&Cox2 enzyme inhibitor. PO, IM, IV, low anti inflammatory effects, for short term acute pain tx, esp post op. SE: GI bleeding.

Answer 11

G: ketorolac

B: Toradol

Question 12

Immunosuppressant, DMARD(TNF blocker) tx of RA, Crohns, UC, psoriasis. SE: bone marrow supp, increase risk of infection,(esp URI), neoplasm,HF, avoid if pt has MS.

Answer 12

G: etanercept

B: Enbrel

Question 13

Analgesic for mild pain, antipyretic. SE: rash, hepatotoxicity with prolonged large doses or overdose.

Answer 13

G: acetaminophen

B: Tylenol, APAP

Question 14

Opioid analgesic, tx of mod to severe pain. Sched II, SE: N&V, constipation, rash, lower Resp, Lower BP, sedation, opioid OD triad, pinpoint pupils, coma

Answer 14

morphine

Question 15

Opioid for mod to severe pain. Esp for biliary pain as it does not cause spasm at the sphincter of oddi. In L&D. Sched II. SE: see morphine. Only use 48hrs as metabolite can cause neurotoxicity & seizures.

Answer 15

G: meperidine

B: Demerol

Question 16

Opioid analgesic. Tx of severe pain. Sched II. Parenteral, transdermal patch, trans mucosal forms. SE: see morphine.

Answer 16

G: fentaNYL

B: Duragesic, Sublimaze

Question 17

Opioid analgesic, slow release. (Every 12 hr PO dosing) Sched II. SE: constipation, respiratory depression, (if resp <12/min, assess level of sedation)

Answer 17

G: oxyCODONE

B: OxyContin.

Question 18

Opioid analgesic, w/acetaminophen, tx of mod pain, also anti tussive effects. Sched III. SE: resp depression, lower BP, sedation, constipation.

Answer 18

G: HYDROcodone/acetaminophen

B: Lortab, Vicodan

Question 19

Opioid agonist/antagonist, tx mod to severe pain. Sched IV, less risk for addiction due to antagonist effect. SE: dizziness, drowsiness, dry mouth.

Answer 19

G: nalbuphine

B: Nubain

Question 20

Analgesic adjuvant, anticonvulsant, also used as mood stabilizer. ESP used for neuropathic pain& migraine prophylactic. SE: drowsiness, lethargy.

Answer 20

G: gabapentin

B: Neurontin

Question 21

Analgesic, anticonvulsant, esp for neuropathic or post herpetic pain. Do not abruptly DC. SE: drowsiness, dry mouth, constipation, poss edema, increase appetite, wt gain

Answer 21

G: pregabalin

B: Lyrica

Question 22

Vascular H/A suppressant, tx of migraine&cluster H/A. For tx not prevention of migraines. SE: transient “chest heaviness”.

Answer 22

G: SUMAtriptan

B: Imitrex