GU Drugs

Question 0

Broad spectrum bacteriostatic & bactericidal. SMZ a sulfa drug. SE: can–> crystalluria so keep well hydrated. Can–> blood dycrasias, also kernicterus in newborn so avoid pregnancy.

Answer 0

G: TMP-SMZ. Trimethoprim+sulfamethoxazole
B: Bactrim, Septra

Question 1

Broad spectrum urinary antiseptic. For acute lower UTI and prophylaxis for recurrent UTI. SE:darkening of urine, rash, H/A, dizziness, peripheral neuropathy.

Answer 1

G: nitrofurantoin

B: Macrodantin

Question 2

Urinary analgesic, relief of pain due to lower urinary tract mucosal irritation. Only use 2 days with antibiotic. SE: GI disturb, rash, turns urine red/orange, stains fabric

Answer 2

G: phenazopyridine

B: Pyridium

Question 3

Bladder muscle stimulant, promotes contraction. Cholinergic effect. Treatment of retention. SE: due to cholinergic effect lower BP, Pulse, increase salivation and diarrhea, bronchoconstriction, asthma flare up.

Answer 3

G: bethanechol

B: Urecholine

Question 4

Bladder relaxant. Antispasmodic, anticholinergic. Tx OAB. SE: dry mouth, eyes & blurred vision. Constipation and urinalysis retention.

Answer 4

G: oxybutynin

B: Ditropan
Also G: solifenacin
B: VESIcare

Question 5

Androgen inhibitor. Tx of benign prostatic hyper trophy. Also hair re growth stimulant. Decrease PSA levels. Could increase r/t cancer. SE: ED

Answer 5

G: finasteride

B: Proscar, Propecia

Question 6

Androgen inhibitor, Tx of BPH. Decrease PSA levels. Could increase r/t cancer. SE: ED, gynecomastia.

Answer 6

G: dutasteride

B: Avodart

Question 7

Alpha blocker, relaxes smooth muscle of bladder neck. Tx of BPH. Decreases obstruction of urethra. SE: orthostatic hypotension, dizziness.

Answer 7

G: tamsulosin

B: Flomax

Question 8

Erectile dysfunction agent. Avoid if taking nitrates. Can have dangerous drop in BP. SE: head ache, flushing, priapism.

Answer 8

G: sildenafil

B: Viagra.

Question 9

Anti hyperuricemic, anti gout. Decreases Uric acid. Prevents Uric acid crystallization. Increase fluid intake. SE: rash, fever.

Answer 9

G: allopurinol

B: Zyloprim

Question 10

Loop diuretic. Produces strong diuresis. Tx of HTN, HF. Encourage foods w/K+. SE: dehydration, hypotension, diarrhea, hypokalemia, leg cramps.

Answer 10

G: furosemide

B: Lasix

Question 11

K+ sparing diuretic. Aldosterone antagonist. Mild diuresis. Tx of HTN, HF. SE: Headache, hyperkalemia, weakness.

Answer 11

G: spironolactone

B: Aldactone

Question 12

Oral potassium replacement supplement. Assess K+ labs.

Answer 12

G: potassium chloride

B: K-Dur