Neoplasia Lecture Review Flashcards
Any abnormal growth of tissue in which multiplication of cells is uncontrolled, more rapid than normal, and progressive
neoplasia
True or False. A neoplasm is synonymous with a tumor
True
True or False. A neoplasm is synonymous with “cancer”
False.
(Remember neoplasia may be benign as well.)
Neoplasia that is slow growing, usually harmless, non-aggressive, non-invasive
benign
Neoplasia that has the ability to spread and metastasize to remote sites in the body
malignant
the multifactoral process by which normal cells are transformed into tumor cells (the process of tumor formation)
Carcinogenesis
physical agents that cause carcinogenesis
Ex: virus, chemical, UV
Carcinogens
normal body tissue that acts a framework and grows blood vessels which nourish the tumor
the stroma
Most tumor cells are ______________, resulting from the progeny of a single cell line
monoclonal
Tumors have a loss of _____________________________________, meaning tumor cells just continue to divide, no matter how crowded the conditions become!
contact inhibition
Neoplastic cells appear differently than normal cells microscopically. Describe how they appear
monoclonal
multiple nucleoli
small cytoplasm
multiple mitotic figures
the process by which cancer cells spread from a primary tumor to secondary locations, such as lung, lymph nodes or visceral sites
metastasis
True or False. Benign tumors are incapable of causing disease.
False.
Remember, disease is any deviation from normal. Benign tumors CAN impede normal function of tissue through their physical presence.
Tumors are composed of two types of tissue:
- parenchyma (the functional tissues of the organ)
- stroma (supporting structures of lymph, blood vessels, connective tissue)
tumors that arise from epithelial tissue
carcinoma
