natural toxins Flashcards

1
Q

natural toxins are found in

A

bacteria
molds/fungi
plants
animals

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2
Q

adaptation of natural toxins through

A

coevolution

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3
Q

plant toxins on skin cause

A

allergic reactions

dermatitis

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4
Q

plant toxins in lungs cause

A

allergic reactions

pneumonia

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5
Q

plant toxins in GI tract cause

A

gasteroenteritis

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6
Q

plant toxins on cardiovascular system cause

A

arrythmia

vasoconstriction

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7
Q

plant toxins in liver cause

A

hepatocyte necrosis

cancer

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8
Q

plant toxins on kidney cause

A

cancer

tubular degeneration

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9
Q

plant toxins on nervous system cause

A

neruotransmission

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10
Q

toxin found in tobacco and used to be used as an insecticide

A

nicotine

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11
Q

toxin found in black pepper

A

piperine

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12
Q

toxin found in jalopenos

A

capsaicin

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13
Q

toxin found in poppy flowers

A

opium/morphine

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14
Q

toxin found in weed

A

THC

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15
Q

stinging nettle has what toxin

A

formic acid

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16
Q

rash that develops from being injected with formic acid

A

urticaria

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17
Q

oily toxin found in poison ivy that can easily penetrate skin

A

urushiol

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18
Q

how is urushiol toxic

A

binds to dermal cells and activates T cells causing an allergy development

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19
Q

natural N-containing bases, both plant and animal derived

A

alkaloids

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20
Q

what type of toxicant is an alkaloid

A

neurotoxicant

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21
Q

toxin found in belladonna and jimson weed that is an acetylcholine receptor antagonist

A

atropine

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22
Q

how is atropine toxic

A

dilates pupils

hallucinations

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23
Q

atropine is an antidote for

A

organophosphorous toxication

24
Q

toxin found in tree laburnam with toxic effects similar to nicotine

25
cytisine is a
actylcholine receptor agonist
26
how is cystine toxic
causes respiratory failure
27
toxin found in hemlock and yellow pitcher plant
coniine
28
how is coniine toxic
muscle paralysis | cholinergic receptor antagonist
29
toxin found in heliotropium, crotolaria, and ragwort that have a bitter taste and protect against herbivores
monocrotaline
30
metabolites of monocrotaline are very reactive causing
veno-occlusive disease mutagenic liver cirrhosis
31
monoterpene oil found in pennyroyal plant, peppermint, and catnip that is essential in perfume and aromatherapy
pulegone
32
how is pulegone toxic
caues uterine contractions , abortions
33
toxin found in castor oil plant
ricin
34
ricin causes
severe acute diarrhea and vomiting
35
ricin protein has two domain what do each do
domain B anchors to cell surface | domain A causes protein synthesis inhibition on ribosome
36
toxin found in the bracken fern which is a herbal remedy against parasitic worms
ptaquiloside
37
what type of cancer does ptaquiloside cause
throat and stomach cancer
38
ptaquiloside contains this that breaks down thiamine
thiaminase
39
vitamine B1 deficiency
beriberi
40
stopc ETC
cyanides
41
cyanides found in almonds peaches and apples
amygdalin
42
cyanides found in cassava
linamarin
43
fungus on rye is an alkaloid
ergot
44
how is ergot toxic
causes vasoconstriction in extremities and abortion
45
toxins found in mushrooms
alpha-amanitin
46
how is alpha-amanitin toxic
causes liver and kidney failure
47
toxins are found in animal groups
``` arthropods molluscs reptiles fish mammals ```
48
affect prey cardiac system, mainly to lower the blood pressure
phosphodiesterases
49
causes prey to lose control of its muscles
cholinesterase inhibitors
50
increases tissue permeability to increase the rate that other enzymes are absorbed into the prey's tissues
hyaluronidase
51
snake venom often contains ____ which are used for breaking down ATP to disrupt the prey's energy fuel use
ATPases
52
puffer fish have this toxin in their skin and intestines which blocks sodium channels on axons
terodotoxin
53
how is terodotoxin toxic
heart failure | respiratory failure
54
two big microbial toxins
botulinum | tetanus
55
extremely toxic and prevents the release of acetylcholine causing paralysis
botulinum
56
blocks release of GABA and glycine causes muscle spasms
tetanus