Natsumi - Botanicals Flashcards
Aconitum napellus
- indication
- Safety profile
- C/I
I: Neuralgia (trigeminal n.), fever/chills 🤕
HIGHLY TOXIC!!
- Tingling sensation in the extremities, rapid chilly, vomits, and diarrhea.
CI: pregnancy, lactation
Tropane alkaloids are found in which herbs?
Atropine belladonna, Datura, and hyoscyamine
Aconite
Trigeminal herbs
Gelsemium and Aconitum
Tropane alkaloid action& Side effects
Anti-cholinergic aka “fight or flight”
Flushed face, dry mucous membrane. mydriasis, blurred vision, giddiness, delirium,
“Hot as hare, red as a beet, dry as a biscuit, blind as a bat, mad as a hatter”
Atropa belladonna action
- Antispasmodic - Myalgia
- Vasoconstrictor
Atropa belladonna Contraindication and drug interaction
C/I: BPH, closed-angle glaucoma, tachycardia, arrhythmia
Drug interaction: TCAs & other anticholinergics
Avena Sativa interaction (internal/external).
Who should not take this?
Internal:
- Nutritive → Anxiety, nicotine/opiate withdrawal, rheumatism
- Fiber → hypercholesterolemia
- Sedative → insomnia
External: anodyne → eczema
C/I: Celiac dz
Interaction: Statins 9decrease effectiveness of HMG-CoA reductase inhibitors)
Eat 2-4 hours AFTER statins
Bacopa monnieri
Constituent: Triterpenoid saponins
Action: Neuroprotective/Antioxidant → cognition/memory, anxiety, epilpsy,
S/E: palpitation, nausea, dry mouth thirst
Safe!
Camelia sinensis action
Cancer preventative and dental caries
S/E: think of coffee, so adding milk reduces s/e
CI: Caffeine → Pregnancy/lactation, insomnia
Centella asiatica
Triterpene acids
Nervine → anxiety, memory, epilepsy, venous insufficiency
Antipyretic → skin
S/E: skin irritation, caution with diabetes or hyperlipidemia can increase blood glucose and lipids
CI: Pregnancy
Datura stramonium
Tropane alkaloids
Sedative antispasmoic
anticholinergic
S/E: same as atropa family
What does atropa a family potentiate
Anticholinergic drugs. do not take wit TCA
Eschscholzia californica
Nervine, hypnotic, anti-spasmodic/anodyne
Sedative and hypnotic for overexcitement and sleepness
S/E: ADDICTIVE* → ‘think of poppy’
C/I: Pregnancy, lactation
Interaction: Potentiates MAOI’s & SSRI
Gelsemium sempverirens
Cholinergic herb
- Stimulates then depress CNS function → induce labor,
- Antispasmodic → cardioprotective, HA, fever, insomnia, and pain
It’s for someone with flu (HA, fever, pain) that can’t sleep.
Side effect: SLEEPY, TOXIC
C/I: Pregnancy & hypotension
Interaction: potentiate aspirin
Humulus lupulus
Action: Sedative nervine, bitter, phytoestrogen, cholegogue, mild laxative
Mood, insomnia, menopaue
SE: ‘beer’ → nausea and HA
C/I: ‘beer’ makes you depressed, pregnant,
InteractionL potentiate sedative-hypnotic effect of barbituates
Hyoscyamus niger
- Indication/Action
- Safety profile
- C/I
- Drug interaction
Tropane alkaloids = Anticholinergic
Sedative → irritability, insomnia, delirium
Antispasmodic → dyspeptic, cough
S/E: anticholinergic side effect + death by choking
C/I: BPH, close angle glaucoma, tachycardiac arrhythmias
Interacts: potentiates anticholinergic drug; TCAs
Hypericum perforatum
External - skin
Internal- depression & anxiety
S/E: photosensitivity rash,
C/I: Suicidal ideation and pregnancy
Interactions:
- Don’t use with psych meds!
- CYP450 inducer!
CYP450 Inducer Herbs
Commiphora mukul
Hypericum perforatum
Tannins
Atimicrobial
Flavenoids
Anti-inflammatory
Cardiac glycosides
Used for CHF and irregular rhythm
Alkaloids
Anti-inflammatory, analgesic, antimicrobial
Disulphides
Reduces iodine uptake by the thyroid (goitergenic)
Seen in Allium Cepa contraindication for HYPOthyroidism
Constituent:
- Lectin
- Indole alkaloids (reserpine)
Hypotensive
Lectin - Viscum album/flavescens
Indole alkaloid - Rauwolfia serpentina
Lecithin
Hypercholesterol
Terpenes
Anti-inflammatory, antioxidant
Melissa officinalis
Volatile oil
Sedative → Calms the limbic system (emotion)
Antispasmodic → tachycardia and palpitations
Carminative → dyspepsia
Topical → skin irritation
C/I: hyperthyroidism & GERD
Matricaria recutita
Constituent:
- Volatile oil
- Chamomile -
yaceae family
Anti-microbial and anti-inflammatory, hypnotic, nervine, sedative
Skin, GI calming, HENT-itis, anxiety/insomnia
Safe!
Asteraceae family
Achillea millefolium Arctium lappa Arnica Montana Artemisa annua/absinthum/vulgariss Calendula officinalis Cineraria maritima Cynara scolymus Echinacea species Eupatorium perfoliatum Eupatorium purureum Grindelia robusta Inula helium Matricaria recutita Silybum marianum Solidago odora Tanacetum parthenium Tanacetum vulgare Taraxacum officinalis Tussilago farfara
Carminative
Relieves flatulence
Passilfora incardnata
Flavonoid
Nervine/Sedative → insomnia, anxiety
Antispasmodic → spasm, convulsions, palpitations and tachycardia
C/I: Uterine stimulant → Pregnancy
Interaction: Psych meds
Piper methysticuicum
Kava “milder weed” - Low dose -
Muscle relaxant/antispasmodic → Neuralgia
sedative/anxiolytiv →Anxiety
S/E: ADDICTIVE, hepatotoxicity,
C/I: Pregnancy/lactation & depression (suicidal)
Interaction: potentiates anti-psychotics
Piscidia erythrina
- Jamaican dogwood - Low dose-
Sedative → Anxiety, fear
analfesic/anodyne → Myalgia
S/E: n/v, CNS depressant, respiratory depression, HF, death
C/I: Pregnancy
Interaction: Potentiate sedative
Pulsatilla vulgaris
Protoenemonin - LOW DOSE -
Nervine→ pain, insomnia,anxiety , HA
Sedative
Emmenagogue → Amenorrhea, dysmenorrhea, endometriosis, PMS, leucorrhea
S/E: Skin irritation, SEVERE GI irritation orally
C/I: Pregnancy
Rhodiola rosea
Adaptogen → depression, faitgue
Anti-cancer
Cardioprotective → im[roving physical endurance
C/I: Manic patien
Interaction: stimulants
Scutellaria lateriflora
Flavonoids
Hypnotic/Nervine → insomnia, anxiety, pain
A/E: hepatotocirt tremor
Safe!
Tanacetum parthenium
- Feverfew - Asteraceae family
Anti-inflammatory/Vasodilator - Migraines, RA, irregular menses
Topical antiseptic
Bitter: GI
S/E: blood thinning
C/I: Pregnancy
Interactions: antagonize morphine, potentiate warfarin
Safe!
Valeriana Officinalis
- 2 Main actions and its indications
- Side effect and safety profile
Sedative: insomnia, anxiety, epilepsy
Anodyne/spasmolytic: muscle spasm
S/E: drowsiness, HA, vertigo,, CNS paralysis
C/I: DO NOT MIX with hepatotoxic agents - EtOH, opioid, barbituates, benzo
Fucus vesiculosis
- Kelp -
Contains: iodine
Iodine → Iodine eficiency hypothyroidism, goiter, obesity, AntiRA
S/E: Hyperthyroism, acne, decrease iron absroption
CI: Hyperthyroidism, pregnancy/lactation
I: Anticoagulants, antiplatelet, thrombolytic agent → increases bleeding
Gymnema sylvestre
- 2 Main actions and its indications
- Side effect and safety profile
Hypolipidemic → Hypercholesterolemia
Anti-obesity → DM, weight loss
I: Potentiate hypoglycemic drugs
Safe!
“Sylvester stallone goes to the gym to get fit”
Lycopus virginicus
LOW DOSE
Blocks T4 to T3 → hyperthyroidism
Cardiac sedative → arrhythmia
Nervine → anxiety, insomnia
C/I: Hypothyroidsim, pregnancy, infertility
Interaction: Levothyroxine
Momordica charantia
- Indications (2)
- Safety profile
- Interaction
- Bitter Melon -
1. Hypoglycemic effect → DM
2. Psoriasis
S/E: allergy
C/I: Emmenagogue, lactation, hypoglycemia
Interaction: Hypoglycemic drugs
“Momo-chan likes bitter melon”
Achillea millefolium
Volatile Oil
Asteraceae family!!
Hemostatic: Hemorrhage/meno-/metorrhagia
Bitter: biliary insufficiency
Diaphoretic; fever
Anti-inflammatory: wound and skin ulcers (topically)
C/E: GERD, digestive stimulation, pregnancy
Interaction: PPI
Capsella bursa-pastoris
Volatile Oil
Astringent /styptic → nose bleed, PMS, wounds/burns
S/E: NA
C/I: Pregnancy
Ineraction: Potentiate Warfarin
Geranium maculatum
Tannins
Astringent/styptic → GI ulcer bleed, hemorrhoids, wounds, heavy menses
S/E: Nausea
C/I: None
Interaction: Tannin → Decrease drug absorption