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Physiology > Nagi's 3rd Lecture BLOOD > Flashcards

Nagi's 3rd Lecture BLOOD Flashcards

1
Q

DNA nuclic acids

A 
Good CAT
cytosine
Guanine 
thymine
Adenine
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2
Q

What is thr difference between megaloblast

And megalocyst

A

The megalocyst has no nucleus

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3
Q

What is the name of the anemia that caused lack of B12 or B9

A

Megaloblastic anemia

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4
Q

What are the properties of megaloblastic anemia

A

Nermochromic
Macro cystic
Less numbers
Less life spam

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5
Q

What is the name of the carries protein of the B12

A

Transcublamin 2

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6
Q

Where is the b12 absorbed in the intestine and which bile it needs

A

In thr lower ilium qns it needs pancreatic bile

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7
Q

What does the iron needs to get absorbed

A

HCL

Vit C

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8
Q

Which beta globulin carry the iron in the blood

A

Transferrin

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9
Q

In which form the iron is stored

A

Ferritin

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10
Q

What is the main regulator iron absorption hormone and from where it is produce

A

Hepecidin

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11
Q

What does the hepecidin do

A 
It is an inhibitor of iron absorption 
When it is high it
 Decreases the number of feropoitin
 Decrease releasing of macrophages that breakdown RBCs
Decrease iron releases form the liver
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12
Q

Why does the infection cause anemia

A

Because it stimuli the hepecidin

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13
Q

What are the symptoms of the heomosidrosis

A

Skin pigmentation and pancreas damage cause prozen diabites

Liver cirrhosis

Testicle
Heart brain damage

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14
Q

What are the causes that prevent iron absorption

A 
Acholrhydria (no HCL)
Dueduneum disease 
Excess
1- ca++
2- tea or coffee
3- phytic acid
بالبر و القمع بقشرو
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15
Q

What is the worm that cause iron deficiency

A

Ankylostome

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16
Q

What is the RBCs number that we can call it anemia in males

A

4.5 million/mm3

17
Q

What is the RBCs number that we can call it anemia in females

A

3.9 million/mm3

18
Q

What is the amount of the HP that we call the person has anemia
Male and female

A

2.5g less the maximum in normal
Males 13.5g/dl
Female 11.5g/dl

19
Q

What is the characteristics of the iron deficiency anemia

A

Microcytic

Hypochromic

20
Q

What are intrinsic defects that leads to hemolytic anemia

A 
1- in membrane 
Inhibitory sphero cytosis
2- HP shape 
Sickle shaped anemia
3- glucose-6-phosphate dehydrogenase enzyme deficiency 
البقوليات بتساعد في تكسير الانزيم
21
Q

What are the extrinsic defects that cause hemolytic anemia

A 
ABCD
Antibodies.    difference blood type
Bacterial toxins 
Chemical positions like snakes 
Drugs as side effect

Physiology (15 decks)

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