Nagi's 2nd Lecture BLOOD Flashcards
What is the volume of the eryntrocytes
90 micro meter cubical
How many RBCs we have in the blood
Women and men
4-5 millions /mm cubical female
5-6 millions/mm cubical men
Why does the infants have more RBCs
Due the lack of the iron they keep getting their need for recycling the erythrocytes till the 4th month
What happens in the incompetabile blood transfusion
The RBCs will blow up and the hemoglobina will be in the blood directly
Which will leads to :
Heart failure
due to increased Blood viscosity and increase the osmotic pressure because we have more molecules now in the blood
Kidney failure
Due to blockage if the tubes
Where are the formation sites of the RBCs in the
Fetus
Child
Adult
In liver and spleen
All bones
Membranous bones
What do we get after breaking down the RBCs
a.a
Iron
Bilirubin
What is the amount of the hemoglobin in the blood
Female
Male
Infant
13-14 gram / deciliter
15-16 gram/dl
19 gram/ dl
Deciliter = 1/10 liter
What is oxidated hemoglobin
The hp that has ferric iron instead if ferrus so we need antioxidation to get it back
What is called the HP that attached to feric not ferruse
Meth HP
What is called thr enzyme the transferring meth HP to normal HP
NADH met.HP reducease
What is called the disease that has less amount of hemoglobin
Thalassemia
When does the sickle shaped anemia
Take the abnormal shape
In the low oxygen levels ONLY
What is the name of the hormone the stimuli RBCs formation
Erythropoietin
Erythropoietin formation sites
In
Adults
Fetus
Adults
85% kidney
15% liver
Fetus
Only liver
What does stimuli erythropoietin with explanation
HYPOXIA
A- alkalines,adinose , adrogean
القلويات تثبط التنفس و بالتالي تجمع ثاني اوكسيد الكربون يلي هو قاعدي و بذلك hypoxia
ال adinose تبع ال ATO بدو اوكسيجن
Adrogean هرمون الذكور
B-beta-adrenigic stimuli
لانو البيتا ريسيبتر بيثبط كل شي ماعدا القلب الايض و الهرمونات و الerythropoietin هرمون
C-cobbalt لانو موجود ب b12
