myocarditis Flashcards
what is it
acute inflammation of the myocardium
causes
- idiopathic
- infective
- toxic
- autoimune
- alcohol
- hydrocarbons
what are the infective causes
- adenovirus
- HIV
- polio
- parasites
- bacterial (streptococcus, diphtheria)
- lyme disease
- fungal
what are the toxic causes
- drugs
- penicillin
- radiation
what are the autoimmune causes
- giant cell myocarditis
- autoimmune form
what is the most common cause in the west
Coxsackie or adenoviral infection
what is Chagas’ disease due to
trypansoma cruzi
what is the pathology of the acute phase
heart is flabby with focal haemorrhages
what is the pathology of chronic phase
heart is enlarged and hypertrophied
what is seen histologically
inflammatory infiltrate is present
what predominates with viral causes
lymphocytes
what predominates with bacterial causes
polymorphonuclear
what predominates with allergic and hypersensitivity causes
eosinophils
symptoms
- asymptomatic
- fatigue
- palpitations
- chest pain
- dyspnoea
- fulminant congestive cardiac failure
physical examination
- soft heart sounds
- prominent third sound
- tachycardia
- pericardial friction rub may be heard