congenital heart disease - atrial septal defect, ventricular septal defecft Flashcards
how often do they occur
in about 1% of all live births
who is more likely to get it women or men
men
which diseases are more common in females
- atrial septal defect
- persistent ductus arteriosus
how is oxygen and nutrients supplied to the foetus
via the placenta and umbilical vein
where does the blood go
half to the fetal ductus venous and carried to the IVC
other half enters the liver
where does the blood move after the IVC
the right atrium
what is significant about foetal heart
there is an opening between right and left atrium
so blood flows from the right to left
what happens to blood in left ventricle
pumped through the aorta through the internal iliac arteries and re-enters the placenta
where does carbon dioxide go
taken up and enters the mothers circulation
where does the blood form the right atrium go that doesn’t go into the left atrium
enters the right ventricle and is pumped into the pulmonary artery
what is the ductus arterioles
connection between the pulmonary artery and the aorta
how does the foramen ovale close
due to increase in left atrial pressure
when does the ductus arteriosus usually close off
1-2 days after birth
this completely separates left and right systems
when does the umbilical vein and ductus venous close off
within 2-5 days of birth
leaving behind the ligaementum teres and the ligamentum venosus of the liver
what are some causes
- maternal prenatal rubella infection
- maternal alcohol misuse
- maternal drug treatment and radiation
- genetic abnormalities
- chromosomal abnormalities
what does alcohol misuse cause
septal defects
what is Turner syndrome associated with
coarctation of aorta
what is Down syndrome associated with
- septal defects
- mitral and tricuspid valve defects
common symptoms
- central cyanosis
- pulmonary hypertension
- finger clubbing
- paradoxical embolism
- polycythaemia
- growth retardation
- syncope
- squatting
why does cyanosis occur
because of right to left shunting of blood
what disease occurs with cyanosis
Fallots tetraology
why does hypertension occur
large left to right shunt
what tis pulmonary hypertension known as
Eisenmengers reaction
what is finger clubbing associated with
prolonged cyanosis
what can polycythaemia develop secondary to
chronic hyperaemia
what does polycythaemia increase risk of
stroke
when is syncope common
when severe right of left ventricular outflow tract is obstructed
when does syncope occur
in Fallots tetralogy associated with cyanosis
when does squatting occur
Fallots tetraology
what is most common congenital cardiac abnormalities
ventricular septal defect
when left ventricular pressure is higher than right where does blood move
from the left to the right
if large defect what does it lead to
- pulmonary hypertension
- Eisenmengers complex