Mycology Flashcards

1
Q

are fungi pro or eukaryotic

A

eukaryotic

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2
Q

uni vs multicellular fungi

A

uni: yeast
multi: mold and mushrooms

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3
Q

how do fungi get nutrition

A

non-photosynthetic heterotrophs

requires organic substrates to get its carbon for growth
- performs extracellular digestion then absorbs nutrients

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4
Q

saprophytic

A

exists in the environment; lives in dead or decaying organic matter (ex. soil)

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5
Q

parasitic

A

exists within a host

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6
Q

are fungi motile

A

no

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7
Q

what kind of environment do fungi thrive in

A

wet/humid
room temperature
acidic pH

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8
Q

are fungi aerobic or anaerobic

A

aerobic

except yeast - facultative anaerobe

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9
Q

what are predisposing factors for fungal infection

A
  • prolonged antibiotic therapy
  • immunosuppression
  • immaturity/malnutrition
  • endocrine disorders
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10
Q

yeast

A

unicellular, oval or spherical cells that are larger than most bacteria

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11
Q

molds

A

multicellular mycelium

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12
Q

hyphae

A

tubular structure of the growing mycelium

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13
Q

septate vs non-septate

A

hyphae separated by cross-walls vs continuous hyphae with no separations

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14
Q

dematiaceous fungi

A

dark pigmented molds

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15
Q

hyaline fungi

A

non-pigmented molds

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16
Q

conidiophores

A

hyphae that produce conidia for asexual reproduction

17
Q

sporangiophores

A

hyphae that produce spores for asexual reproduction

18
Q

conidia/spores

A

infective stage of mold
- environmentally resistant

released when sporangium ruptures
- allows for aerial dissemination

19
Q

dimorphic fungi

A

fungi that change from mold to yeast depending on environment

ex. thermal
- mold at room temp
- yeast at warm temp

20
Q

sexual vs asexual fungal reproduction

A

sexual: rare; fusion of haploid nuclei then meiosis

asexual: most common; division by mitosis

21
Q

mechanisms of asexual reproduction in fungi

A
  1. sporulation
  2. hyphae fragmentation
  3. budding (yeast only)
22
Q

classification of fungal disease

A
  • superficial (dermatophytosis, dermatomycoses)
  • subcutaneous
  • systemic
23
Q

capsule

A

compact capsule or external coating composed of polysaccharides that aid in adherence or clumping

protects fungi in the host or in the environment
- can be antigenic and anti-phagocytic

24
Q

fungal cell wall

A

lies outside cytoplasmic membrane

composed of polysaccharide chains cross-linked with proteins and glycoproteins
- contains chitin
- different fungal species have common polysaccharides in cell wall

25
Q

fungi cytoplasmic membrane

A

bilayer membrane that contains sterols (ergosterol, zymosterol)

NOT cholesterol like in mammals

26
Q

what is the most common immune response to fungi

A

cell mediated formation of granulomatous lesions
- type IV hypersensitivity

antibodies not effective

27
Q

what must the media used for propagating fungi contain

A

carbon source

28
Q

cutaneous mycoses

A
  • dermatomycoses
  • dermatophytoses
29
Q

dermatomycoses

A

opportunistic infections of skin or mucocutaneous junctions from overgrowth of fungi

ex. malassezia pachydermatis and candida albicans

30
Q

malassezia pachydermatis

A

yeast

causes otitis externa and dermatitis in dogs

31
Q

candida albicans

A

yeast - endogenous; can overgrow esp. in immunocompromised hosts

inhabits mucous membranes of animals and birds

causes yellow/gray plaques and ulceration

32
Q

dermatophytoses

A

subset of dermatomycoses caused only by dermatophytes

invasion and destruction of keratinized structures
- superficial skin, hair, feathers, hooves, claws, etc

ex. ringworm

33
Q

how to diagnose dermatophytosis

A

hair plucks
skin scrapings on edge of lesion

34
Q

chytridiomycosis

A

infectious disease of amphibians casued by batrachochytrium dendrobatidis

affects skin –> decreased ability to breathe, hydrate, osmoregulate

35
Q

white nose syndrome

A

infectious disease of bats caused by pseudogymnokscus destructans