Coronaviruses Flashcards
what are the targets of coronaviruses
GI tract
respiratory tract
systemic
what species are affected by coronaviruses
many
dogs, cats, pigs, cows, horses, camelids, poultry, ferrets
what coronavirus causes systemic illness in its host species
feline coronavirus
structure of coronaviruses
enveloped
ssRNA
club shaped spikes on surface
what are the main proteins that trigger an immune response
S: spike protein
N: nucleocapsid
enteric coronavirus transmission
fecal oral
what is the target of enteric coronaviruses
mature enterocytes at the villus tips
causes villus blunting leading to malabsorption and maldigestion
clinical signs of enteric coronavirus
NOT significant cause of clinical disease due to targeting of the villus tips instead of crypts
causes mild diarrhea
signalment for enteric coronaviruses
neonates due to lack of maternal antibodies
respiratory coronavirus transmission
aerosol
direct contact
what is the target of respiratory coronaviruses
mucociliary escalator
what is a significant predisposing factor to respiratory coronaviruses
overcrowding and stress
