Musculoskeletal Disorders Flashcards
What is the most severe and common type of muscular dystrophy?
Duchenne muscular dystrophy
What is absent in the muscle of children with Duchenne Muscular Dystrophy?
Dystrophin
What is Dystrophin?
A protein product in skeletal muscle that helps the muscles contract and stay toned.
What is pseudohypertrophy?
Muscular englargement caused by fatty infiltration.
What occurs as DMD progresses?
Muscular atrophy.
When do symptoms of DMD generally occur age wise?
3-7 years
What is the progression of DMD?
Weakness to abnormal gait to paralysis
What generally happens by 12 years old to patients with DMD?
They can be wheelchair or bed bound because they have contractures and deformities of small and large joints.
What are some clinical manifestations of DMD?
Waddling, Lordosis, faling, gower sign, pseudohypertrophy, atrophy in later stages, cognitive impairment, contractures, obesity
What is the prognosis of DMD?
Death from respiratory tract infection or cardiac failure- very difficult diagnosis
How is DMD diagnosed?
by blood polymerase chain reaction for dystrophin gene mutation, EMG, and CPK levels, and muscle biopsys
How can DMD be diagnosed prenatally?
If another child has had this problem it can be Dx-ed at 12 weeks
What is an EMG test?
electromyography- painful test that tests for muscle activity in each muscle.
Why are CPK levels high in DMD patients in the first two years of life?
because as the muscle is damages, it elevates CPK
What is the treatment of DMD?
Corticosteroids, PT, Respiratory therapy, bracing, surgery
What are some nursing care techniques with DMD patients?
Supportive care to PT and family, Assess systems, promote self care, educate, provide resources.
What is Osteogenesis Imperfecta (OI)?
Brittle bone disease- an autosomal dominate disease with 6 types.
What are the 6 types of OI?
Mild, lethal, severe, mild to moderate, similar to IV, DX by bone biopsy
What are clinical manifestations of OI?
Increase fractures, fractures at birth, deformities, small stature, blue sclerae, decrease hearing
What is the treatment for OI?
Supportive; light weight braces, rehab therapy, surgery to correct fractures, biophosphate therapy to promote bone density
What is the nursing care for OI?
Be careful and treat fragily, educate parents.