Muscles Flashcards

1
Q

What are the types of muscle

A
  1. Smooth muscle: causes peristalsis
  2. Skeletal muscle: helps us move and breathe
  3. cardiac: contracts our heart
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2
Q

What are characteristics of muscle

A
  1. contractile: causes movement of the body and changes in size/shape of internal organs.
  2. conductive
  3. skeletal muscle is a major source of body heat (by product of cellular respiration)
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3
Q

What are characteristics of skeletal muscle

A
  1. somatic (voluntary)
  2. striated
  3. multinucleated
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4
Q

what are characteristics of cardiac muscle

A
  1. heart
  2. autonomic
  3. striated
  4. single nucleus; centrally placed
  5. intercalated discs
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5
Q

what are characteristics of smooth vessel

A
  1. walls of viscera, blood vessels, skin
  2. autonomic
  3. not striated
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6
Q

diff between smooth muscle and dense irregular CT:

A

You see a lot of nuclei (fusiform or corkscrew) and not a lot of extracellular space. Collagen in ECM stains more darkly with eosin in dense irregular CT

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7
Q

What is organization of a skeletal muscle

A

muscle –> muscle fascicle –> muscle fiber –> myofibrils –>myofilaments

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8
Q

reticular fibers is what type of collagen

A

type 3

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9
Q

describe endomyseum

A
  1. reticular fibers

2. surr ind muscle fibers

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10
Q

describe perimysyium

A
  1. thicker CT
  2. surr muscle fascicles
  3. blood vessel and nerves withim
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11
Q

what are myofibrils

A

contain contractile element of the cell

-extend the entire length of the muscle fiber

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12
Q

myofilaments are arranged in:

A

sarcomores which is a contractile unit; sarcomere shortens with contraction

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13
Q

Sarcomeres:

A

Thin filaments only present in the I band.
A band is in the center.
M line is where other proteins are that anchor the thick filaments together.

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14
Q

A band never changes in ___but the amount they overlap changes

A

length

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15
Q

____bands shorten during contraction

A

I

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16
Q

What are the thin filaments

A
  1. actin
  2. tropomyosin
  3. troponin
17
Q

what is the thick filaments

A
  1. myosin
  2. 2 heavy chains (rod and heavy)
  3. 4 light chains (regulatory)
18
Q

ONly possible with the prescense of calcium

A
  1. Myosin heads bound to thin filament
  2. ATP binds to mysoin head causeing conformation change which releases actin
  3. ATP gets hydrolyzed to ADP and phophate; which causes head to get cocked back
  4. Powerstroke: head reaches up and binds actin which releases inorganic phosphate and ADP; myosin head comes forward again and pulls actin chain
  5. Back to step 1
19
Q

I band =

A

light band

20
Q

A band =

A

dark band

21
Q

H band is the light band witin the

A

A band.

22
Q

During contraction only I band and H band

A

decrease in size; A band is constant

23
Q

What is SR

A

Specialized smooth ER involved in sequesteration of calcium

24
Q

What is T tubule

A

bring depolarization from sarcolemma along SR within skeletal muscle fiber; leads to release of calcium from SR allowing contraction; lined up at interface of I band and A band.

25
Q

What is sarcolemma

A

plasma membrane of muscle fiber which travel all the way down to center of cell

26
Q

where is mitochondria located

A

in periphery and between myofibrils

27
Q

What forms myotubes

A

myoblasts which are made from progenitor cells.

28
Q

Each motor end plate of formed from;

A

presynaptic membrane

29
Q

describe features of muscle spindles

A

Proprioceptive elements to the muscles. They consist of spindle fibers within double capsule. Muscle spindle fibers involved with gamma motor neurons