Muscles Flashcards
What are the types of muscle
- Smooth muscle: causes peristalsis
- Skeletal muscle: helps us move and breathe
- cardiac: contracts our heart
What are characteristics of muscle
- contractile: causes movement of the body and changes in size/shape of internal organs.
- conductive
- skeletal muscle is a major source of body heat (by product of cellular respiration)
What are characteristics of skeletal muscle
- somatic (voluntary)
- striated
- multinucleated
what are characteristics of cardiac muscle
- heart
- autonomic
- striated
- single nucleus; centrally placed
- intercalated discs
what are characteristics of smooth vessel
- walls of viscera, blood vessels, skin
- autonomic
- not striated
diff between smooth muscle and dense irregular CT:
You see a lot of nuclei (fusiform or corkscrew) and not a lot of extracellular space. Collagen in ECM stains more darkly with eosin in dense irregular CT
What is organization of a skeletal muscle
muscle –> muscle fascicle –> muscle fiber –> myofibrils –>myofilaments
reticular fibers is what type of collagen
type 3
describe endomyseum
- reticular fibers
2. surr ind muscle fibers
describe perimysyium
- thicker CT
- surr muscle fascicles
- blood vessel and nerves withim
what are myofibrils
contain contractile element of the cell
-extend the entire length of the muscle fiber
myofilaments are arranged in:
sarcomores which is a contractile unit; sarcomere shortens with contraction
Sarcomeres:
Thin filaments only present in the I band.
A band is in the center.
M line is where other proteins are that anchor the thick filaments together.
A band never changes in ___but the amount they overlap changes
length
____bands shorten during contraction
I
What are the thin filaments
- actin
- tropomyosin
- troponin
what is the thick filaments
- myosin
- 2 heavy chains (rod and heavy)
- 4 light chains (regulatory)
ONly possible with the prescense of calcium
- Myosin heads bound to thin filament
- ATP binds to mysoin head causeing conformation change which releases actin
- ATP gets hydrolyzed to ADP and phophate; which causes head to get cocked back
- Powerstroke: head reaches up and binds actin which releases inorganic phosphate and ADP; myosin head comes forward again and pulls actin chain
- Back to step 1
I band =
light band
A band =
dark band
H band is the light band witin the
A band.
During contraction only I band and H band
decrease in size; A band is constant
What is SR
Specialized smooth ER involved in sequesteration of calcium
What is T tubule
bring depolarization from sarcolemma along SR within skeletal muscle fiber; leads to release of calcium from SR allowing contraction; lined up at interface of I band and A band.