Muscle: skeletal muscle 2 Flashcards
length tension relationship
during an isometric contraction, the maximum active force (tension developed) at the sarcomere is dependent on the overlap of actin and myosin
excitation contraction coupling
- ACh released into neuro-muscular junction
- activation of ACH receptors
- a muscle action potential is triggered
- calcium is released from SR
- Ca binds with troponin -> Crossbridge cycle
- Ca levels fall and contraction ends
muscle metabolism
sources of ATP
1. creatine phosphate - (ATP + creatine stores energy which is then given back as ATP when reacting with ADP, when needed immediately - 15s)
2. anaerobic glycolysis - breakdown of glucose (energy for 2min)
3. aerobic metabolism - mitochondira, energy for several minutes to hours
passive force
increases as the muscle is stretched due to passive elements
active force
developed via cross-bridge cycling: dependent on actin-myosin overlap
motor unit
a motor neuron and all the muscle fibres it connects to and sends signal to
one nerve per muscle fibre but a nerve can connect to multiple fibres
type 1 motor unit
slow twitch - slow efficient aerobic cells for mosture and walking
type 2 motor unit
fast twitch - large fibres that fatigue rapidly but develop large forces for jumping or weight lifting
regulation of force
dependent on
1) rate of stimulation of individual motor units
- single stimulus, contraction and relaxation
- another stimulus before fully relaxed, more tension results
- high frequency of stimuli, no relaxation between, high tension
2) the number of motor units recruited
- greater stimulation means more units recruited gives more tension, where smaller more fatigue resistant units are recruited first